Adam Goodwill | Biomedical Sciences | WVU Health Sciences Center

2006- 07 Ph.D. Students in Biomedical Sciences

Adam Goodwill
	Hometown: North Warren, PA Undergraduate Institution: Clarion University of PA Degree(s): B.S., Molecular Biology/BioTech Biology Research Interests: Relationships between chronic sub-acute inflammation under conditions of elevated cardiovascular risk and alterations to endothelial function. Graduate Program: Cellular & Integrative Physiology Research Advisor: Jefferson Frisbee, Ph.D. Current Position: Postdoctoral Fellow, Indiana University Postdoctoral Research Advisor: Johnathan Hune, Ph.D.

Hometown: North Warren, PA
Undergraduate Institution: Clarion University of PA
Degree(s): B.S., Molecular Biology/BioTech Biology
Research Interests: Relationships between chronic sub-acute inflammation under conditions of elevated cardiovascular risk and alterations to endothelial function.
Graduate Program: Cellular & Integrative Physiology
Research Advisor: Jefferson Frisbee, Ph.D.
Current Position: Postdoctoral Fellow, Indiana University
Postdoctoral Research Advisor: Johnathan Hune, Ph.D.

Published Manuscripts:

1. Frisbee, J.C., Goodwill, A.G., Butcher, J.T. & Olfert, I.M. (2011). Divergence between arterial perfusion and fatigue resistance in skeletal muscle in the metabolic syndrome. Exp Physiol. Mar;96(3):369-83. PMCID: PMC3041869.

2. Adams-Stapleton, P.A., Goodwill, A.G., James, M.E., Brock, R.W., Frisbee, J.C. (2010). Hypercholesterolemia and microvascular dysfunction: interventional strategies. J Inflamm (Lond). Nov 18;7:54. PMCID: PMC2996379.

3. Frisbee, S.J., Chambers, C.B., Frisbee, J.C., Goodwill, A.G. & Crout, R.J. (2010). Self-reported dental hygiene, obesity, and systemic inflammation in a pediatric rural community cohort. BMC Oral Health. Sep 18;10:21. PMID: 20849640.

4. Frisbee, J.C., Goodwill, A.G., Stapleton, P.A., Frisbee, S.J. & d'Audiffret, A.C. (2010). Aspirin resistance with genetic dyslipidemia: contribution of vascular thromboxane generation.Physiol Genomics. Aug;42(3):331-41. PMID: 20530721.

5. Stapleton, P.A., Goodwill, A.G., James, M.E., D'Audiffret, A.C. & Frisbee, J.C. (2010). Differential impact of familial hypercholesterolemia and combined hyperlipidemia on vascular wall and network remodeling in mice.Microcirculation. Jan;17(1):47-58. PMID: 20141600.

6. d'Audiffret, A.C., Frisbee, S.J., Stapleton, P.A., Goodwill, A.G., Isingrini, E. & Frisbee, J.C. (2010). Depressive Behavior And Vascular Dysfunction: A Link Between Clinical Depression And Vascular Disease? J Appl Physiol. May;108(5):1041-51. PMID: 20167667.

7. Samora, J.B., Goodwill, A.G., Frisbee, J.C. & Boegehold, M.A. (2010). Growth-Dependant Changes in the Contribution of Carbon Monoxide to Arteriolar Function. J Vasc Res. 47(1):23-34. PMID: 19672105.

8. Goodwill, A.G, Frisbee, S.J., Stapleton, P.A., James, M.E. & Frisbee, J.C. (2009). Impact of Chronic Anticholesterol Therapy on Development of Microvascular Rarefaction in the Metabolic Syndrome. Microcirculation. Aug 4:1-18. PMID: 19657966.

9. Goodwill, A.G., Stapleton, P.A., James, M.E., D'Audiffret, A.C. & Frisbee, J.C. (2008). Increased arachidonic acid-induced thromboxane generation impairs skeletal muscle arteriolar dilation with genetic dyslipidemia. Microcirculation. Oct;15(7):621-31. PMID: 18720229.

10. Goodwill, A.G., James, M.E. & Frisbee, J.C. (2008). Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension. Am J Physiol Heart Circ Physiol. Oct;295(4):H1522-8. PMID: 18689495.

11. Stapleton, P.A., James, M.E., Goodwill, A.G. & Frisbee, J.C. (2008). Obesity and vascular dysfunction. Pathophysiology. Aug;15(2):79-89. Epub 2008. Jun 20. PMID: 18571908.

12. Stapleton, P.A., Goodwill, A.G., James, M.E. & Frisbee, J.C. (2007). Altered mechanisms of endothelium-dependent dilation in skeletal muscle arterioles with genetic hypercholesterolemia. Am J Physiol Regul Integr Comp Physiol. Sep;293(3):R1110-9. PMID: 17626122.

13. Jones, A.M., Goodwill, A.G. & Elliott, T. (2006). Limited role for the DsrA and RprA regulatory RNAs in rpoS regulation in Salmonella enterica. J Bacteriol. Jul;188(14):5077-88. PMID: 16816180.

Awards:

2009 Microcirculatory Society Zweifach Student Travel Award
Adam Goodwill will be receiving this award, established in 1998 by the Microcirculatory Society (MCS). The award recognizes the outstanding mentoring efforts by Dr. Benjamin W. Zweifach and is designed to encourage meeting participation by young scientists in training. Students (undergraduate, graduate, or medical) who are working in areas related to the microcirculation even if they are not from a laboratory focused on microcirculation research were encouraged to apply. There was a maximum of 10 awards available to students.

Presentations:

1. Goodwill, A.G. Vascular thromboxane generation restrains arteriolar hypoxic dilation in skeletal muscle of obese zucker rats. Experimental Biology Meeting New Orleans, LA. Abstract (poster presentation). 2009.

2. Goodwill, A.G. Increased arachidonic acid-induced thromboxane generation impairs skeletal muscle arteriolar dilation with genetic dyslipidemia. Experimental Biology Meeting New Orleans, LA. Abstract (poster presentation). 2009.