Name: S. Sendhil Velan, Ph.D.

Assistant Professor
Radiology and Center for Advanced Imaging
West Virginia University
One medical Center Drive,
HSC South - 9236
Morgantown, WV – 26506
Phone: 304 – 293 – 1877

Education

Institution Degree year Field of study

University of Madras, India B.Sc 1986 Physics
University of Madras, India M.Sc 1989 Bio-Physics
University of Madras, India M.Phil 1990 Crystallography and Biophysics
University of Madras, India Ph.D. 1997 Biophysics- Chemical Physics

Employment
1990-1991 Research Fellow, Cancer Institute, India
1991-1993 Senior Research Fellow, Council of Scientific and Industrial Research, India
1994-1996 Hindustan Lever Senior Research Fellow, India
1997-1998 NIH post-doctoral fellow, National institute on Aging, NIH, MD
1999-2002 Staff Scientist, Beckman Institute, California Institute of Technology, CA
2003- Present Assistant Professor, Radiology and Center for Advanced Imaging, West Virginia University
2003-Present Visiting Scientist, National Institute on Aging, NIH
2003-Present Visiting Scientist, Chemistry Department, WVU
2004-Present Visiting Scientist, Physics Department, WVU

Professional Memberships
International Society for Magnetic Resonance in Medicine, 1998 - current
Electron Paramagnetic Resonance Society, 1999 - current
American Association of Physicists in Medicine, 2004 -

Publications:

Monitoring the therapeutic response of tumors by Nuclear Magnetic Resonance spectroscopy. S. Sendhil Velan, N.R. Jagannathan, K. Saravanan and B. Nagarajan. Med. Sci. Res., 19, 609-611, 1991.

Therapeutic response of tumors by in vitro proton Nuclear Magnetic Resonance Spectroscopy . N.R. Jagannathan and S. Sendhil Velan Appl. Magn. Reson., 5, 357-367, 1993.

Multiple-Quantum-Single-Quantum NMR Images N. Chandrakumar and S. Sendhil Velan J. Magn. Reson., Series A 104, 115-118, 1993.

Separation of Longitudinal Multispin Order by Frequency Cycling. N. Chandrakumar and S. Sendhil Velan J. Magn. Reson., Series A 104, 363-365, 1993.

Novel NMR experiments to measure self-diffusion coefficients in solution. S. Sendhil Velan and N. Chandrakumar Proceedings of the Indian Academy of Sciences (Chemical Sciences) 106, 1661-1669, 1994. Diamond Jubilee special issue on Magnetic Resonance.

High Resolution NMR measurement of Molecular self-diffusion by Fast Multi- Spin-Echo Diffusion sequences. S. Sendhil Velan and N. Chandrakumar J. Magn. Reson., Series A 123, 122-125, 1996.

Electron paramagnetic resonance oxygen mapping (EPROM): Direct visualization of oxygen concentration in tissue S. Sendhil Velan, Richard G.S. Spencer, Jay L. Zweier, Kuppusamy Magn. Reson. Med., 43, 804-809, 2000.

MR Imaging with Phase Encoding of Intermolecular Multiple Quantum Coherences . S. Sendhil Velan, P.T. Narasimhan and Russell E. Jacobs J. Magn. Reson., 152, 189-194, 2001.

EPR Oxygen Mapping (EPROM) of Engineered Cartilage Grown in a Hollow Fiber Bioreactor Scott J. Ellis, M. Velayutham, S. Sendhil Velan, Erik F. Petersen, Jay L. Zweier, Periannan Kuppusamy, and Richard G.S. Spencer Magn. Reson. Med. 46, 819-826 , 2001

Micro-MRI at 11.7T of a Murine Brain Tumor Model Using Delayed Contrast Enhancement Moats, R.A., S. Sendhil Velan, Russell Jacobs, Gomez G, I, Dobowitz, D.J., Taga T.,Khankaldyyan,V., Schultz L., Fraser S.,Nelson, M.D.,and Laug, WE
Molecular Imaging, 2, 150-158, 2003.

Analysis of longitudinal multispin orders in strongly coupled spin systems
S. Sendhil Velan J. Magn. Reson., 171, 345-352, 2004.

Recent Conference Presentations:

Mapping the distribution of lactate in cartilage grown in cartilage grown from chondrocytes in a hollow fiber bioreactor. ISMRM workshop on connective tissues and Biomaterials, 1998. S. Sendhil Velan E. Petersen, K.W. Fishbein, and R.G.S.Spencer.

Effect of therapeutic agents on matrix formation in cartilage. ISMRM workshop on connective tissues and Biomaterials, 1998.
E. F. Petersen, S. Sendhil Velan, K. Potter, W. Horton and R.G.S. Spencer

3D-MR microscopy of the mouse brain with intermolecular zero and double quantum coherences at 11.7T, ISMRM 2000.
P.T. Narasimhan, S. Sendhil Velan and Russell E. Jacobs

A multimodal, multidimensional atlas of the C57Bl/6 mouse brain. Neuroscience, 2001, San Diego. A.Mackenzie-Graham, E. Lee, S. Sendhil Velan et al.

3D Time-Lapse Analysis of Xenopus Gastrulation Movements Using µ-MRI C. Papan, S. Sendhil Velan, S.E. Fraser, and R.E. Jacobs
Developmental Biology, 235, 89, 2001.

Magnetic resonance microscopic imaging of mouse brain by phase encoding intermolecular double quantum coherences
S. Sendhil velan, P.T. Narasimhan, R. Pautler, and R.E. Jacobs. Presented at ISMRM 2002

MR microscopy with intermolecular double quantum coherences S. Sendhil Velan, P.T. Narasimhan and R.E. Jacobs
Presented at ENC 2002.

Investigation of Muscle Metabolism by Multi-Dimensional Localized Magnetic Resonance Spectroscopic Techniques at 3T
S. Sendhil Velan, Susan Lemieux, Raymond Raylman, Albert Thomas
Presented at 21st ICMRBS, 2005

Novel Probes for Magnetic Resonance Imaging
A. Manivannan and S. Sendhil Velan
Presented at 21st ICMRBS, 2005

Unraveling Glutathione and other low Concentration Cerebral Metabolites using 2D Correlated Spectroscopy on a 3T MRI Scanner.
S. Sendhil Velan, S. Ramamurthy, Susan Lemieux, R.R. Raylman, M. Albert Thomas
Presented at ISMRM, 2005.

Reliable detection of GABA and Glutathione by novel localized two-dimensional correlated MRS techniques in the brain at 3T
To be presented at EPR 2005.

Grants:

1.Research Development Grant, West Virginia University

Metabolite characterization and quantification in Tumors: 1D and 2D Localized Magnetic Resonance Spectroscopy
PI: S. Sendhil Velan

2. WVU Research Corporation, West Virginia University

Acquisition of Magnetic Resonance Microscopic imaging System for establishing multi-disciplinary research interfacing basic sciences and clinical sciences at WVU.
Role:Co-Investigator