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Gregory Dick, Ph.D.

Immunocytochemical staining shows potassium channel expression (red) in cultured cells (nuclei are blue). The level of channel expression is decreased by shRNA (short hairpin RNA).

Han-Gang Yu, Ph.D.

Increased phosphorylation of the channel protein by Src tyrosine kinase promoted surface expression of HCN4

Paul Chantler, Ph.D.

Dr. Paul Chantler conducts a resting echocardiogram to visualize heart function.

Robert Brock, Ph.D.

Color maps of the kidney microcirculation illustrating the significant disparity in the flow of blood between diabetic and non-diabetic mice.

Emidio Pistilli, Ph.D.

Dr. Emidio Pistilli analyzes force production and fatigue responses of muscles isolated from mouse models of disease.

Gerald Audet, Graduate Student

Jerry from Dr. Mark Olfert's laboratory is testing a cell death enzyme-linked immunosorbent assay (or you can just say ELISA). He is investigating how the protein Thrombospondin-1 induces apoptosis and reduces capillarity in skeletal muscle.

Jefferson Frisbee, Ph.D.

Image (viewed through a standard dissecting microscope) of the gracilis muscle resistance arteriole prior to surgical isolation and removal for in vitro study.

Phoebe Stapleton, Ph.D.

Dr. Stapleton, postdoctoral fellow, studies the systemic microvascular consequences of pulmonary muti-walled carbon nanotube exposures

WVU Hockey Team

Let’s go Mountaineers...!!


Congratulations to Sophie...!!

Congratulations to Sophie on American Heart Association Grant...!!

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Congratulations to Justin...!!

Congratulations to Graduate Fellow, Justin Chamber

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Research Team

Research team examines the dangers and potential of nanomaterials

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Message From The Director

Welcome to the Center for Cardiovascular and Respiratory Sciences (CCRS) at the West Virginia University Health Sciences Center! We are an evolving interdisciplinary center housed within the WVU HSC and are comprised of research investigators and educators spanning three main campuses of WVU; the Health Science Center, Evansdale and Downtown. Within this, we have core members of the CCRS in the following Colleges and Schools:

Eberly College of Arts and Sciences
School of Dentistry
Benjamin M. Statler College of Engineering and Mineral Resources
School of Medicine
School of Nursing
School of Pharmacy
College of Physical Activity and Sport Sciences
School of Public Health
Center for Neuroscience

We have three major components to our integrated mission as a center:

Research: Recently, the CCRS has targeted its research mission around three major themes:

  • Xenobiotic Toxicology
  • Cardiovascular Disease Risk Factors
  • Chronic Stress, Depression and Cardiovascular Disease

In addition, we are actively working with the Center for Neuroscience and Dr. James Simpkins, Director of the Center for Basic and Translational Stroke Research, to help develop and establish the ‘cardiovascular’ components underlying stroke research.

Education: our CCRS faculty members are all actively engaged in not only contributing to the ongoing educational mission of WVU, they are also continually developing new, state-of-the art, educational opportunities for students across the academic spectrum. For more information on these efforts, please contact Dr. Fred L. Minnear, Associate Dean for Graduate Studies, or visit our Office for Research and Graduate Education.

Service: In addition to the ongoing service to the academic community and scientific societies in which all of our faculty participate, our service to the state and residents of West Virginia occurs primarily through the public health/outreach efforts in each of our three research themes. These public health/outreach efforts within the research themes have their own experienced leadership to help facilitate their activities.

We thank you for your interest in visiting our website and learning more about our center. If we can provide you any additional information about educational and research opportunities within the CCRS through its myriad efforts, please do not hesitate to contact us at your earliest convenience.

Jefferson C. Frisbee, Ph.D.
Director, Center for Cardiovascular and Respiratory Sciences
Professor, Department of Physiology and Pharmacology

BMS 793: Translational Cardiovascular Sciences Summer Course (53104)
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