Anoop Shankar, M.D., M.P.H., Ph.D.
	Associate Professor of Epidemiology Graduate Training: University of North Carolina Fellowship: University of Wisconsin-Madison
	Office: Room G103 P.O. Box 9190 Morgantown, WV 26506-9190	Email: ashankar@hsc.wvu.edu Phone: 304-293-0199 Fax: 304-293-6685

Research Interests:

1. Epidemiology of cardiovascular diseases, diabetes mellitus, hypertension, chronic kidney disease
2. Role of inflammation, endothelial dysfunction, oxidative stress, and microvascular disease in the development of CVD, Diabetes Mellitus
3. Clinical proteomics in subclinical measures of cardiovascular disease, hypertension and chronic kidney disease

I am involved in several large population-based cohort studies in the US (Beaver Dam cohort, ARIC) and internationally (University of Sydney, Australia [Blue Mountains cohort study], and National University of Singapore, Singapore). There is a nested case-control study on the relation between markers of inflammation, endothelial function, oxidative stress and incident chronic kidney disease (longitudinal data over 20 years). Also several projects are ongoing where we use data from the NHANES surveys to look at cardiovascular disease risk factors, peripheral arterial disease and hypertension. Also new population-based studies are being developed in WV.

• Sleep characteristics and Sleep Disordered Breathing in relation to cardiovascular disease

Longitudinal cohort study data from the Wisconsin Sleep cohort; sleep duration and sleep characteristics data available in the some of the national surveys (NHIS for example). Also we are developing new studies in WVU.

• International Health (particularly CVD and diabetes epidemiology)

I am involved in a large ongoing cohort study of 63000 men and women of Chinese ethnicity from Singapore to study the role of dietary factors in cardiovascular disease and diabetes mellitus.

Selected Peer-Reviewed Articles:

1. Shankar A, Koh WP, Yuan JM, Lee HP, Yu MC. Sleep duration and coronary heart disease mortality among Chinese adults in Singapore: A population-based cohort study. American Journal of Epidemiology. 2008 Dec 15; 168 (12) 1367-73.
2. Shankar A, Li J. Positive association between high-sensitivity C-reactive protein level and diabetes mellitus among US non-Hispanic black adults. Experimental & Clinical Endocrinology and Diabetes.2008 Sept;116:455-460.
3. Shankar A, Li J, Klein BEK, Nieto FJ, Klein R. Serum gamma-glutamyltransferase level and peripheral arterial disease. Atherosclerosis. 2008 Jul;199(1):102-9.
4. Shankar A, Wang JJ, et al. Positive association between plasma homocysteine level and chronic kidney disease. Kidney & Blood Pressure Research. 2008;31(1):55-62.
   Shankar A, Li J, Marshall S. Association between plasma adiponectin level and hypertension. Acta Cardiologica.2008 April; 63 (2): 160-5.
5. Shankar A, Li J. Association between serum gamma-glutamyltransferase level and prehypertension among US adults. Circulation J. 2007 Oct;71(10):1567-72.
6. Shankar A, Li J, Nieto FJ, Klein BE, Klein R. Association between C-reactive protein level and peripheral arterial disease among US adults without cardiovascular disease, diabetes, or hypertension. Am Heart J. 2007 Sep;154(3):495-501.
7. Shankar A, Klein R, Klein BE, Moss SE. Association between glycosylated hemoglobin level and cardiovascular and all-cause mortality in type 1 diabetes. American J Epidemiology. 2007 Aug 15;166(4):393-402.
8. Shankar A, Mitchell P, Rochtchina E, Tan J, Wang JJ. Association between circulating white blood cell count and long-term incidence of age-related macular degenaration. American J Epidemiology. 2007 Feb 15;165(4):375-82.
9. Shankar A, Wang JJ, Rochtchina E, Mitchell P. Positive association between plasma fibrinogen level and incident hypertension among men. Population-based cohort study. Hypertension. 2006 Dec;48(6):1043-9.
10. Shankar A, Klein R, Klein BEK, Nieto FJ. The association between serum uric acid level and long-term incidence of hypertension: population-based cohort study. J of Human Hypertension. 2006 Dec;20(12):937-45.
11. Shankar A, Klein R, Klein BEK. The association among smoking, heavy drinking, and chronic kidney disease. Am J Epidemiology. 2006 Aug 1;164(3):263-71.
12. Shankar A, Mitchell P, Rotchina E, Wang JJ. Association between circulating white blood cell count, triglyceride level and cardiovascular and all-cause mortality. Results from the Blue Mountains Eye Study. Atherosclerosis. 2007 May;192(1):177-83.
13. Shankar A, Wang JJ, Rochtchina E, Yu MC, Mitchell P, Kefford R. Positive association between circulating white blood cell count and cancer mortality: Population-based cohort study. Arch Intern Med. 2006 Jan 23;166(2):188-94.

Resarch Based Media Releases:

WV Public Radio:WVU doctor studies sleeping habits and heart health.

WV Health Reports on Feb 23 Evening News in WBOY-TV 12 News: Sleep and Heart Disease