West Virginia University, Robert C. Byrd Health Sciences Center
Center for Cardiovascular and Respiratory Sciences
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Principal Investigators

Dr. Frisbee with Microscope

NAME AREA OF INTEREST
Matthew A. Boegehold, Ph.D.

Effect of dietary salt and hypertension on microvascular control mechanisms.

Robert W. Brock, Ph.D.
Regulation of renal and hepatic microvascular environments in diabetes and/or systemic inflammation.
Stephen E. Alway, Ph.D., F.A.C.S.M.

Mechanisms and treatment for apoptosis-induced cardiac and skeletal muscle wasting in aging.

James A. Antonini, Ph.D. Health effects associated with the inhalation of aerosols (e.g., welding fume, fly ash, silica, asbestos) generated in the workplace.
Alex d'Audiffret , M.D. Endovascular interventions including aortic endografts, carotid stenting, renal stenting


Paul Chantler, Ph.D.


The effects of aging and CV diseases on arterial and ventricular structure and function.

Richard Dey, Ph.D. Neuroanatomical organization and embryological development of airway innervation, examining interconnections between airway neurons and airway structures (smooth muscle, blood vessels, glands, epithelium), and on determining neuronal responses to inhaled irritants.
Gregory Dick, Ph.D.

Regulation of ion channels in vascular smooth muscle

Geri Dino, Ph.D. Adolescent smoking cessation, child obesity prevention, and program and system-level evaluation
Jeffrey S. Fedan, Ph.D. Regulation of airway reactivity by the airway epithelium, in health and in models of human lung disease such as asthma and occupational asthma
Mitch Finkel, M.D. Cardiac responses to ischemic and non-ischemic injury: Molecular and cellular mechanisms.
Jefferson C. Frisbee, Ph.D. Alterations to microvascular structure and function during metabolic syndrome development.
Stephanie J. Frisbee, Ph.D. Policy and epidemiologic approaches to pediatric cardovascular health outcomes.
Pingnian He, M.D., Ph.D. Regulation of leukocyte-endothelium interactions and microvascular permeability.
John Hollander, Ph.D. Heat-shock proteins, transgenic models, ischemia reperfusion injury in the heart.
Kim Horn, EdD, MSW Population health disparities, community-based partipatory reseearch, tobacco intervention, systems evaluation.
Jason Huber, Ph.D. Understand the role of the neurovascular unit in neurological health and disease.
Travis Knuckles, Ph.D.

Role of inhaled particulate matter and nanoparticles in microvascular dysfunction and autonomic nervous system changes.

Kevin T. Larkin, Ph.D. Cardiovascular, cognitive, and behavioral responses to stress.
Jun Liu, Ph.D. Molecular regulation of endothelial cell growth, migration and differentiation in angiogenesis.
Shyama Masilamani, Ph.D. Renal hemodynamics, renal sodium transporters and channel regulation, blood pressure control, kidney in pregnancy. 
Michael R. Miller, Ph.D.

Interaction of the spirochete that causes Lyme disease, Borrelia burgdorferi (Bb) with the cardiovascular system, including how Bb causes inflammation, interaction of Bb with blood cells and endothelial cells and how Bb penetrates blood vessels. We also study the molecular mechanisms regulating Bb chemotaxis and motility.

Fred Minnear, Ph.D. Cellular mechanisms regulating protein permeability across pulmonary vascular endothelium.
Sam Mukdadi, Ph.D.
Nonlinear harmonic contrast imaging, Diagnostic and therapeutic ultrasound, Broadband ultrasound transducer design, Cardiovascular biomechanics, Ultrasonic nondestructive evaluation , Micro- and Nano- material characterization
S. Jamal Mustafa, Ph.D. Cellular and molecular mechanisms of coronary blood flow regulation .

Mohammed A. Nayeem, Ph.D.

Regulation of vascular tone through CYP epoxygenases, soluble epoxide hydrolase and omega hydroxylase.
William A. Neal, M.D.
Role of lipids and cholesterol in coronary heart disease.
Timothy R. Nurkiewicz, Ph.D.
Mechanisms underlying the microvascular dysfunction triggered by air pollution and nanoparticle exposure.
I. Mark Olfert, Ph.D. Pulmonary gas exchange , oxygen transport, exercise-induced angiogenesis, skeletal muscle structure and function.
Emidio Pistilli, Ph.D. Skeletal and cardiac muscle dysfunction in disease states and aging; muscle mechanics and contractility; role of interleukins in muscle phenotypes.
Lisa M. Salati, Ph.D. Nutrient regulation of cellular function and metabolism. Molecular mechanisms involved in the regulation of gene expression and hormone action.

Michael Schaller, Ph.D.

Molecular mechanisms controlling signaling events important for angiogenesis and endothelial cell responses to mechanical stimulation.

Anoop Shankar, Ph.D.
Cardiovascular diseases, diabetes mellitus, hypertension, chronic kidney disease.
Role of inflammation, endothelial dysfunction, oxidative stress, microvascular disease in the development of CVD, Diabetes Mellitus.
Influences of host and environmental factors on pulmonary inflammatory and immune responses.
William Wonderlin, Ph.D.  
Robert Wysolmerski, Ph.D.

Endothelial Cell Contraction , Actin Cytoskeleton and Lung Vascular Permeability

Han-Gang Yu, Ph.D.

Cardiac ion channels.

Center for Cardiovascular and Respiratory Sciences
P.O. Box 9105 | Morgantown, WV 26506-9105
Last Modified: February 2, 2012
© 2012 West Virginia University.