West Virginia University, Robert C. Byrd Health Sciences Center
Center for Cardiovascular and Respiratory Sciences
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Principal Investigators

Dr. Frisbee with Microscope

NAME AREA OF INTEREST
James A. Antonini, Ph.D. Health effects associated with the inhalation of aerosols (e.g., welding fume, fly ash, silica, asbestos) generated in the workplace.
Matthew A. Boegehold, Ph.D.

Effect of dietary salt and hypertension on microvascular control mechanisms.

Robert W. Brock, Ph.D.
Regulation of renal and hepatic microvascular environments in diabetes and/or systemic inflammation.
Stephen E. Alway, Ph.D., F.A.C.S.M.

Mechanisms and treatment for apoptosis-induced cardiac and skeletal muscle wasting in aging.

Alex d'Audiffret , M.D. Endovascular interventions including aortic endografts, carotid stenting, renal stenting
Richard Dey, Ph.D. Neuroanatomical organization and embryological development of airway innervation, examining interconnections between airway neurons and airway structures (smooth muscle, blood vessels, glands, epithelium), and on determining neuronal responses to inhaled irritants.
Gregory Dick, Ph.D.

Regulation of ion channels in vascular smooth muscle

Geri Dino, Ph.D. Adolescent smoking cessation, child obesity prevention, and program and system-level evaluation
Jeffrey S. Fedan, Ph.D. Regulation of airway reactivity by the airway epithelium, in health and in models of human lung disease such as asthma and occupational asthma
Mitch Finkel, M.D. Cardiac responses to ischemic and non-ischemic injury: Molecular and cellular mechanisms.
Jefferson C. Frisbee, Ph.D. Alterations to microvascular structure and function during metabolic syndrome development.
Pingnian He, M.D., Ph.D. Regulation of leukocyte-endothelium interactions and microvascular permeability.
John Hollander, Ph.D. Heat-shock proteins, transgenic models, ischemia reperfusion injury in the heart.
Kim Horn, EdD, MSW Population health disparities, community-based partipatory reseearch, tobacco intervention, systems evaluation.
Jason Huber, Ph.D. Understand the role of the neurovascular unit in neurological health and disease.
Bing-Hua Jiang, Ph.D. Role of the PI 3-kinase signaling pathway in angiogenesis.
Kevin T. Larkin, Ph.D. Cardiovascular, cognitive, and behavioral responses to stress.
Jun Liu, Ph.D. Molecular regulation of endothelial cell growth, migration and differentiation in angiogenesis.
Michael R. Miller, Ph.D.

Interaction of the spirochete that causes Lyme disease, Borrelia burgdorferi (Bb) with the cardiovascular system, including how Bb causes inflammation, interaction of Bb with blood cells and endothelial cells and how Bb penetrates blood vessels. We also study the molecular mechanisms regulating Bb chemotaxis and motility.

Fred Minnear, Ph.D. Cellular mechanisms regulating protein permeability across pulmonary vascular endothelium.
Michael R. Morissette, Ph.D. Role of myostatin (or growth differentiation factor-8) in cardiac hypertrophy and failure.
Priscah Mujuru, Ph.D. Environmental and occupational health that focuses on special populations that includes children and the elderly.
Sam Mukdadi, Ph.D.
Nonlinear harmonic contrast imaging, Diagnostic and therapeutic ultrasound, Broadband ultrasound transducer design, Cardiovascular biomechanics, Ultrasonic nondestructive evaluation , Micro- and Nano- material characterization
S. Jamal Mustafa, Ph.D. Cellular and molecular mechanisms of coronary blood flow regulation .

Mohammed A. Nayeem, Ph.D.

Regulation of vascular tone through CYP epoxygenases, soluble epoxide hydrolase and omega hydroxylase.
William A. Neal, M.D.
Role of lipids and cholesterol in coronary heart disease.
Timothy R. Nurkiewicz, Ph.D.
Mechanisms underlying the microvascular dysfunction triggered by air pollution and nanoparticle exposure.
I. Mark Olfert, Ph.D. Pulmonary gas exchange , oxygen transport, exercise-induced angiogenesis, skeletal muscle structure and function.
Frank Reilly, Ph.D. Microcirculatory factors responsible for low flow, progressive cellular injury and death in diabetes.
Lisa M. Salati, Ph.D. Nutrient regulation of cellular function and metabolism. Molecular mechanisms involved in the regulation of gene expression and hormone action.
Michael Schaller, Ph.D.  
Anoop Shankar, Ph.D.
Cardiovascular diseases, diabetes mellitus, hypertension, chronic kidney disease.
Role of inflammation, endothelial dysfunction, oxidative stress, microvascular disease in the development of CVD, Diabetes Mellitus.
Influences of host and environmental factors on pulmonary inflammatory and immune responses.
David Williamson, Ph.D. Regulation of muscle function and morphology in obesity
Robert Wysolmerski, Ph.D.

Endothelial Cell Contraction , Actin Cytoskeleton and Lung Vascular Permeability

Han-Gang Yu, Ph.D.

Cardiac ion channels.

Center for Cardiovascular and Respiratory Sciences
P.O. Box 9105 | Morgantown, WV 26506-9105
Last Modified: August 25, 2009
© 2009 West Virginia University.