▪▪ NIH/NCI R01CA192064 (PI: Khramtsov), 08/01/2015-07/31/2020
Profiling chemical tumor microenvironment: application for diagnostics & therapy.
This project will develop the innovative magnetic resonance approaches for multifunctional in vivo tumor microenvironment profiling in a mouse model of breast cancer to identify prognostic factors and monitor tissue microenvironment manipulation. This will provide necessary background data for further studies aimed to improve the accuracy with which the clinical behavior of a given lesion can be predicted, and optimize efficacy of the tumor microenvironment-targeted therapeutic interventions.
▪▪ NIH/NCI R01 CA194013 (MPI: Khramtsov and Eubank), 04/01/2015-03/31/2020
In vivo monitoring of tumor microenvironment regulation by macrophages.
This project is aimed to prove the hypothesis that bi-directional interaction between tumor microenvironment and macrophages plays significant role in tumor progression and therapy efficacy.
▪▪ K25 EB016040 (PI: Tseytlin), 09/01/13-08/31/16
Enhancing in vivo EPR imaging using spin probes with short relaxation times.