The Molecular Medicine Core Facility was established in April 2005 as the focal point of cancer genetics and genotyping to support basic and translational research and also to provide guidance for treatment of clinical trails in the Cancer Center. This core facility contains automated equipment necessary for sequence DNA. The core is staffed by a director (Jing Jie Yu, MD) and a technician who receive tissue or cell samples, and can purify mRNA (polyA+ RNA), make cDNA copies of specific genes and analyze the sequence by cDNA sequence analysis. The Core houses specialized equipment including state-of-the-art CEQ 8000 capillary DNA Sequencer (Beckman Coulter) with the capacity to analyze 96 samples and to provide consistent and accurate sequencing data, and the ABI Thermal Cyclers (models 9600 and 9700) used in studies of gene expression and cycle sequencing, etc.

Our 10 years of experience in genomics investigation and genetic analysis enables investigators in reaching their research and treatment goals. The objective of this Core is to provide advanced technical services and expertise for all investigators in the WVU HSC in designing and conducting the proper experiments, preparing appropriate samples for analysis, performing essential assays such as RT-PCR, Real-Time PCR, DNA Sequencing and SNP, and assisting in correct interpretation of generated data.

For more information on Molecular Medicine at West Virginia University please visit this link: http://www.hsc.wvu.edu/mbrcc/research/molecularMedicineCore/index.asp

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