Sharon L.Wenger

Education:

Undergraduate

• Thiel College 1971

Medical School

• University of Pittsburgh, 1976

Training:

Fellowship

• Children's Hospital of Pittsburgh 1980

Certification

• American Board of Medical Genetics

Focus

• Clinical Cytogenetics

Research Interests:

• Telomere Rearrangements
• Chromosome Breakage Syndromes
• X Inactivation
• Chromosome Mosaicism

Selected Publications:

1. Herring DB, Harbert KA, Wenger SL, Ericson SG. Acquired Robertsonian translocations in leukemia – two more cases. Cancer Genet Cytogenet 2005;158:196-197.
2. Evdokimova VN, McLoughlin RK, Wenger SL, Grant SG. Use of the glycophorin A somatic mutation assay for rapid unambiguous identification of Fanconi anemia homozygotes regardless of GPA genotype. Am J Med Genet 2005;135A:59-65.
3. Wonsettler DM, Chang WWL, Wenger SL. Extra copy of 20q deletion, acute myelomonocytic leukemia (M4) and Niemann-Pick disease. J Assn Genet Technol 2005;31:55-58.
4. Jeffries AR, Curran S, Elmslie F, Sharma A, Wenger S, Hummel M, Powell J. Molecular and phenotypic characterization of ring chromosome 22. Am J Med Genet 2005;137A:139-147.
5. Grant SG, McLoughlin RK, Wenger SL. Unusual pattern of bone marrow somatic mutation in pediatric patients referred for cytogenetic analysis. Balkan J Med Genet 2005;8:45-51.
6. Tang W, Wenger SL. Cell death as a possible mechanism for tissue limited mosaicism in Pallister-Killian syndrome. J Assoc Genet Technologists 2005;31:168-169.
7. Yu M, Obringer AC, Fowler MH, Hummel M, Wenger SL. Prenatal detection of deletion 6q13q15 in a complex karyotype. Prenatal Diagn 2005;25:1084-1087.
8. Wenger SL, Grossfeld PD, Siu BL, Coad JE, Keller FG, Hummel M.  Molecular characterization of an interstitial deletion in a patient with the 11q terminal deletion disorder.  Am J Med Genet 2006;140A:704-708.
9. Wang Y, Wiltshire T, Senft J, Wenger SL, Reed E, Wang, W. 2006. Fanconi anemia D2 protein confers chemoresistance in response to anticancer agent, irofulven. Molecular Cancer Therapeutics 2006;5:3153-3161.
10. Wiltshire T, Senft J, Wang Y, Konat GW, Wenger SL, Reed E, Wang W.  BRCA1 contributes to cell cycle arrest and chemoresistance in response to anticancer agent, irofulven. Mol Pharmacol 2007;71:1051-1060.
11. Tomchin SB, Perrotta PL, Wenger SL. A 40-year-old man with easy bruising and bone pain.  Department of Pathology, WVU. Case of the Month March, 2007. http://www.hsc.wvu.edu/som/pathology/07casearchives/apcasemar07/apMar07.asp
12. Livengood RH, Coad JE, Wenger SL.  48 year-old woman with a lymphoproliferative disorder.  Department of Pathology Case of the Month December 2007. http://www.hsc.wvu.edu/som/pathology/cases/apcasedec07/apdec07.asp
13. Wenger SL, Cottrell S, Ducatman BS.  Classroom versus online learning: experience with pathology remedial course.  J IAMSE 2007;17:83-86.
14. Wise JL, Hummel M, Wenger SL.  Inheritance of subtelomeric deletions and the importance of ruling out familial polymorphic variants. J Assoc Genet Technologists 2008;34:89-91.
15. Hartel PH, Shackelford AL, Hartel JV, Wenger, SL.  Del(5q) is associated with clinical and histological parameters in small cell lung cancer.  Int J Surg Pathol 2008;16(4):419-23.
16. Oliverio BJ, Canfield PA, Wenger SL.  A 53 year-old female evaluated for knee replacements. Department of Pathology Case of the Month November 2008. http://www.hsc.wvu.edu/som/pathology/cases/apcasenov08/apnov08.asp
17. Bailey NG, Wenger SL, Grant MR. A 45-year old male with abdominal pain.  Department of Pathology Case of the Month February 2009 http://www.hsc.wvu.edu/som/pathology/cases/apcasefeb09/apfeb09.asp
18. Wise JL, Crout RJ, McNeil DW, Weyant RJ, Marazita ML, Wenger SL.  Cryptic subtelomeric rearrangements and X chromosome mosaicism: a study of 565 apparently normal individuals with fluorescent in situ hybridization, PLoS ONE, 2009; e5855.               doi:10.1371/journal.pone.0005855.
19. Wise JL, Crout RJ, McNeil DW, Weyant RJ, Maraziat ML, Wenger SL.  Human telomere length correlates to the size of the associated chromosome arm. PLoS ONE, 2009;4(6): e6013. doi:10.1371/journal.pone.0006013.