| Health Center | Address | State | County | CIS |
| Bluestone Health Assoc. - Bluestone Health Center | 3997 Beckley Road, Princeton, WV 24740 | WV | Mercer | CDEMS |
| Bluestone Health Assoc. - Prudich Medical Center | PO Box 736, Montcalm, WV 24737 | WV | Mercer | CDEMS In-process |
| Braxton County Hospital | 100 Hoylman Drive, Gassaway, WV 26624 | WV | Braxton | CDEMS |
| Browning Family Practice | PO Box 470, Hillsboro, WV 24946 | WV | Pocahontas | CDEMS |
| Cabin Creek Health Center | 102 Sharon Road, Dawes, WV 25331 | WV | Kanawha | CDEMS/EMR |
| Cabin Creek Health Center--Clendenin | 301 Elk River Road, Clendenin, WV 25045 | WV | Kanawha | CDEMS/EMR |
| Cabin Creek Health Center--Sissonville | 7133 Sissonville Drive, Sissonville, WV 25320 | WV | Kanawha | CDEMS/EMR |
| Camden-On-Gauley Medical Center, Inc. | 10003 Webster Road; PO Box 69, Camden-On-Gauley, WV 26208 | WV | Webster | CDEMS |
| Central West Virginia Community Health Center | 55 Friends-R-Fun Drive, Summersville, WV 26551 | WV | Nicholas | CDEMS In Process |
| Change, Inc. | 3136 West Street, Weirton, WV 26062 | WV | Hancock | EMR |
| Clay-Battelle Health Services Association | 5861 Mason Dixon Hwy, Blacksville, WV 26521 | WV | Monongalia | CDEMS |
| Community Health Foundation of Man | 600 East McDonald Avenue, Man, WV 25635 | WV | Logan | CDEMS |
| E.A. Hawes Health Center - Baker | PO Box 97, Baker, WV 26801 | WV | Hardy | EMR |
| E.A. Hawes Health Center - Mathias | PO Box 132, Mathias, WV 26812 | WV | Hardy | EMR |
| Family Care - Hinton | 197 Pleasant St, Hinton, WV 25951 | WV | Summers | CDEMS In-process |
| FamilyCare | 301-6 Great Teays Blvd, Scott Depot, WV 25560 | WV | Putnam | PECS |
| Harpers Ferry Family Medicine | 171 Taylor St., Harpers Ferry, WV 25425 | WV | Jefferson | EMR |
| Lincoln Primary Care Center, Inc. | 7400 Lynn Avenue, Hamlin, WV 25523 | WV | Lincoln | PECS |
| Madison Medical Center | 705 Madison Avenue, Madison, WV 21530 | WV | Boone | EMR |
| Minnie Hamilton Health Care Center | 186 Hospital Drive, Grantsville, WV 26147 | WV | Calhoun | EMR |
| Monongahela Valley Association of Health Centers - Fairmont Clinic | 1322 Locust Ave, Fairmont, WV 26554 | WV | Marion | CDEMS/EMR |
| Monongahela Valley Association of Health Centers - Fairview | 400 Main Street, Fairview, WV 26570 | WV | Marion | CDEMS/EMR |
| Monongahela Valley Association of Health Centers - Shinnston | 1 Columbia Road, Shinnston, WV 26431 | WV | Marion | CDEMS/EMR |
| Monroe Health Center | PO Box 590, Union, WV 24983 | WV | Monroe | PECS |
| New River Health Association - Beard's Fork | 735 Beards Fork Road, Robson, WV 25173 | WV | Fayette | CDEMS/EMR |
| New River Health Association - Breathing Center | PO Box 377, Scarbro, WV 29517 | WV | Fayette | CDEMS/EMR |
| New River Health Association - Fayetteville | 221 West Maple Ave., Fayetteville, WV 25840 | WV | Fayette | CDEMS/EMR |
| New River Health Association - Lisa Elliot Center | , Lookout, WV 25868 | WV | Fayette | CDEMS/EMR |
| New River Health Association - Robinson Annex | Rt. 1 Box 615A, Whipple, WV 29517 | WV | Fayette | CDEMS/EMR |
| New River Health Association - Scarbro | Old Scarbro Road, PO Box 337, Scarbro, WV 25917 | WV | Fayette | CDEMS/EMR |
| New River Health Association - Whipple | Rt. 1 Box 615A, Whipple, WV 29517 | WV | Fayette | CDEMS/EMR |
| Northern Greenbrier Health Center | PO Box 10, Williamsburg, WV 24991 | WV | Greenbrier | CDEMS |
| Pocahontas Memorial Hospital | RR2, Box 52W, Buckeye, WV 24924 | WV | Pocahontas | EMR |
| Preston-Taylor Community Health Centers (Grafton) | PO Box 399, Grafton, WV 26354 | WV | Taylor | CDEMS |
| Preston-Taylor Community Health Centers (Mt Storm) | , , WV 26739 | WV | Grant | CDEMS |
| Preston-Taylor Community Health Centers (Newburg) | PO Box 159, Morgantown Street, Newburg, WV 26410 | WV | Preston | CDEMS |
| Primary Care Systems, Inc. | PO Box 147, Clay, WV 25043 | WV | Clay | EMR |
| Rainelle Community Health Center | 645 Kanawha Ave., Rainelle, WV 25962 | WV | Greenbrier | EMR |
| Ritchie County Primary Care Association | 135 S Penn Ave, Harrisville, WV 26362 | WV | Ritchie | CDEMS/EMR |
| Roane County Family Health Care | 146 Williams Drive, Spencer, WV 25276 | WV | Roane | CDEMS/EMR |
| Robert C Byrd at WVSOM | 400 North Jefferson St., Lewisburg, WV 24901 | WV | Greenbrier | EMR |
| Shenandoah Valley Medical System, Inc. | 99 Tavern Road, PO Box 1146, Martinsburg, WV 25402 | WV | Berkeley | EMR |
| St. George Medical Clinic | Route 1, Box 208, St. George, WV 26287 | WV | Tucker | CDEMS |
| Tug River Health Association, Inc. | PO Box 507, Gary, WV 24836 | WV | McDowell | CDEMS/EMR |
| Urgent Care of Elkins | 1 Pleasant Ave, Suite 1, Elkins, WV 26241 | WV | Randolph | CDEMS |
| Valley Health Care, Inc. | PO Box 247, Mill Creek, WV 26280 | WV | Randolph | EMR |
| Westmoreland Clinic | 2908 Auburn Road, Huntington, WV 25704 | WV | Wayne | CDEMS In-process |
| Wheeling Health Right | 61 29th Street, Wheeling, WV 26003 | WV | Ohio | EMR |
| Williamson Memorial (Family Medical) | 859 Alderson Street / P.O. Box 1980, Williamson, WV 25661 | WV | Mingo | CDEMS |
| Wirt Co. Health Services Assoc. - Coplin Memorial | 1301 Elizabeth Pike, Elizabeth, WV 26143 | WV | Wirt | CDEMS/EMR |
| Wirt Co. Health Services Assoc. - River Valley | 606 Washington St., Ravenswood, WV 26164 | WV | Jackson | CDEMS/EMR |
| WVU Charleston - Medicine and Specialty Office | 4522 MacCorkle Ave., SE, Suite 3, Charleston, WV 25304 | WV | Kanawha | CDEMS/EMR |
| Johnson & Johnson Diabetes Institute | 1001 South Milpitas Boulevard, Milpitas, CA 95035 | CA | Santa Clara | CDEMS |
| Westmed Family Healthcare | 12001 Pecos St, Denver, CO 80234 | CO | Adams | CDEMS |
| Westminster Family Healthcare | 8601 Turnpike Drive #200, Denver, CO 80031 | CO | Adams | CDEMS |
| Pediatric Endocrine Associates | 1100 Lake Hearn Drive, Suite 350, Atlanta, GA 30342 | GA | Fulton | CDEMS |
| DuPage Community Clinic | 1506 East Roosevelt Road, Wheaton, IL 60187 | IL | DuPage | Considering registry use |
| American Health Network | 4880 Century Plaza Road, Suite 200, Indianapolis, IN 46254 | IN | Marion | CDEMS |
| Silver City Health Center | 3015 Strong , Kansas City, KS 66106 | KS | Wyandotte | CDEMS |
| Muhlenberg Community Hospital | 440 Hopkinsville St. , Greenville, KY 42345 | KY | Muhlenberg | CDEMS |
| Holy Cross Hospital | 1500 Forest Glen Rd, Silver Spring, MD 20910 | MD | Montgomery | CDEMS |
| Johns Hopkins Bloomberg School of Public Health | 601 N. Caroline Street , Baltimore, MD 21287-0760 | MD | Baltimore City | CDEMS |
| Rural Health Group, Inc. | P.O. Box 250; 108 N. Mosby Avenue, Littleton, NC 27850 | NC | Halifax | CDEMS |
| Akron Children's Hospital Mahoning Valley | 100 DeBartolo Place, Suite 115 , Boardman, OH 44512 | OH | Mahoning | CDEMS |
| East Ohio Regional Hospital | 90 North 4th Street, Martins Ferry, OH 43935 | OH | Belmont | CDEMS |
| Genesis Respiratory Health Clinic | 2951 Maple Ave., Zanesville, OH 43701 | OH | Muskingum | CDEMS |
| Oklahoma - Central Oklahoma Family Medical Center | 527 West 3rd, Konawa, OK 74849 | OK | Seminole | CDEMS/EMR |
| Oklahoma - Community Health Connection | 9912 E. 21st St., Tulsa, OK 74129 | OK | Tulsa | CDEMS/EMR |
| Oklahoma - Fairfax Medical Facilities | 212 North Main, Fairfax, OK 74637 | OK | Osage | CDEMS/EMR |
| Oklahoma - Family Health Center of Southern OK | 610 East 24th Street, Tishomingo, OK 73460 | OK | Johnston | CDEMS/EMR |
| Oklahoma - Great Salt Plains Health Center | 400 S. Ohio, Cherokee, OK 73728 | OK | Alfalfa | CDEMS/EMR |
| Oklahoma - Hominy Family Health Center | 409 N. Eastern Ave., Hominy, OK 74035 | OK | Osage | CDEMS |
| Oklahoma - Kiamichi Family Medical Center | 500 Main Street, Battiest, OK 74722 | OK | McCurtain | CDEMS |
| Oklahoma - Kiamichi Family Medical Center at Idabel | 601 Washington Street, Idabel, OK 74745 | OK | McCurtain | CDEMS |
| Oklahoma - Lawton Community Health Center | 3811 W. Gore Blvd., Suite 6, Lawton, OK 73505 | OK | Comanche | EMR |
| Oklahoma - Mary Mahoney Memorial Health Center | 12716 N.E. 36th Street, Spencer, OK 73084 | OK | Oklahoma | CDEMS/EMR |
| Oklahoma - Morton Comprehensive Health Services | 1334 North Lansing Avenue, Tulsa, OK 74106 | OK | Tulsa | CDEMS/EMR |
| Oklahoma - Northeast OK Community Health Center | 124 East Main St., Holbert, OK 74441 | OK | Cherokee | EMR |
| Oklahoma - Pushmataha Family Medical Center | 109 Stanely Road, Clayton, OK 74536 | OK | Pushmataha | EMR |
| Oklahoma - South Central Medical & Resource Center | 210 NW 4th St., Lindsay, OK 73052 | OK | Garvin | EMR |
| Oklahoma - Stigler Health and Wellness | 1407 NE D Street, Stigler, OK 74462 | OK | Haskell | EMR |
| Oklahoma Primary Care Association | 4300 North Lincoln Blvd., Ste. 203, Oklahoma City, OK 73105 | OK | Oklahoma | - |
| Altoona Regional Health System | Altoona Hospital Campus - OP-2, 620 Howard Avenue, Altoona, PA 16601 | PA | Blair | CDEMS |
| Lungs at Work | 4000 Waterdam Plaza Dr., Suite 120, McMurray, PA 15317 | PA | Allegheny | CDEMS |
| Partner Respiratory Care & Health and Wellness | 600 Somerset Avenue, Windber, PA 15963 | PA | Somerset | CDEMS |
| Rhode Island Department of Health | 3 Capitol Hill, Room 408, Providence, RI 02908 | RI | Providence | CDEMS |