David Weissman

Academic Interests:

Dr. Weissman's research interests relate to understanding the influences of host and environmental factors on pulmonary inflammatory and immune responses. He is particularly interested in antibody responses to inhaled and aspirated antigen. Two model systems are currently being used to study pulmonary immunity in his laboratory. The first uses intrapulmonary instillation of antigen via a bronchoscope to study human pulmonary immunity, with current studies focusing on understanding pulmonary immunotoxic effects of cigarette smoking. The second uses an animal model of the occupational lung disease silicosis to study abnormal pulmonary immunomodulation of antibody production and cellular immunity in this condition.