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Department of Pathology
Case of the Month June 2002
52 year-old female with a thyroid gland nodule
Dana Wonsettler M. D., Barbara Ducatman M. D.
Microscopic Description
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Figure 3 (10x) |
Figure 4 (40x) |
Figure 5 |
Figure 3 H&E Low Power. Round to polygonal cells in a somewhat lobular pattern of growth. Notice the amorphic eosinophilic stroma.
Figure 4 H&E High Power. Polygonal cells with abundant pink granular cytoplasm, oval nuclei, speckled chromatin, and inconspicuous nucleoli. Multiple binucleate cells are present.
Figure 5 Congo Red. Prominent staining with Congo red is seen in the stromal deposits.
Figure 6 (a & b) Congo Red Photographed in Polarized Light. Stromal deposits exhibit characteristic green birefringence.
Figure 7 Calcitonin Immunoperoxidase. Strong positivity is exhibited with calcitonin staining.
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