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Department of Pathology

Case of the Month February 2003

A 16 YEAR OLD FEMALE WITH SEVERE BLEEDING AFTER A MINOR FALL

Darren Harris, MD, and Patricia Canfield, MD

 

Laboratory Tests

Test Name (units) Patient Result Normal Range    
WBC (X103/UL) 7.6 3.5-11.0  
RBC (X106/UL) 3.6 3.8-5.2  
Hemoglobin (g/dL) 10.5 11.2-15.2  
Hematocrit (%) 31.9 33.5-45.2  
Platelets
(X103/UL)
273 140-450  
PT (sec) 11.1 9.5-12.5  
PTT (sec) 42.2 24.8-37.3  
       
Platelet Function Analysis:      
Collagen:Epinephrine (sec) >300 94-193  
Collagen:ADP (sec) >300 71-118  
Factor VIII
(% of normal)
39 50-150  
Ristocetin Cofactor Activity 36 70-116  
vWF Antigen (% of normal) 34 50-150  

Agarose Gel Electrophoresis of plasma vWF:

Normal Patient