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Department of Pathology
Case of the Month September 2006
A 12 year old boy with a pineal region tumor
James V. Hartel MD, Kymberly A. Gyure MD
Microscopic Examination
Microscopic examination revealed polygonal neoplastic cells with large, vesicular nuclei and prominent nucleoli. There was an accompanying lymphocytic infiltrate and areas of microcalcification (Fig. 1 and 2) were present. Immunohistochemistry revealed that the large polygonal cells were positive for placental alkaline phosphatase (PLAP) and negative for β-human chorionic growth factor (β-hCG) and alpha-fetoprotein (AFP) (not shown).
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Figure 1 |
Figure 2 |
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