Meningeal hemangiopericytomas account for less than 3% of all meningeal tumors. They may arise from either spinal or cranial dura mater. Unlike meningiomas, which have female predilection, the tumor occurs in genders with equal frequency. Peak incidence is in the fourth decade of life. Clinical symptoms may be due to compression, local invasion, or distant metastasis. Those occurring around the jugular foramen cause lower cranial neuropathies. Microscopically, the tumor cells are tightly packed and arranged around an elaborate vasculature. Typically, the dividing sinusoidal vessels have a “staghorn” configuration. The cells are positive for CD34 and vimentin and negative for S-100 protein and EMA. Treatment is with surgical resection, usually with pre-operative embolization. Postoperative radiation increases survival. Tumors may metastasize, and regrowth is typical
References
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