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John G. Thomas, MS, PhD

Selected Publications

Presentations
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2008

  • Preshaw, P M, Novak, M J ,Mellonig J, Magnusson, I, Polson, A,  Giannobile W        V, Rowland, R W, Thomas, J G, Walker C, Dawson, D R , Sharkey, D and Bradshaw, MH.  Modified-release subantimicrobial dose doxycycline enhances scaling and root planning in patients with periodontal disease.  Journal of Periodondology …..March , 2008

2007

  • Cross,Jenny L., Ramadan, Hassan H., and Thomas , John G.  (2007)  The impact of a cation channel blocker (furosemide) on Pseudomonas aeruginosa PA01 biofilm architecture .Otolaryngology-Head and Neck Surgery . 137 (1):21-26.Oxley, K S, Thomas, J G, Ranadan, H H (2007).  Effect of ototopical medications on tympanostomy tube biofilms. Laryngoscope 117 (10):1819-24.
  • Thomas, John G Nakaishi, Lindsay and Corum, Linda .Consequences of Biofilms on Indwelling Medical Devices:  Cost and Prevention,p.  289-334,   in Disinfection and Decontamination , Principles , Applications and Related Issues.  Ed, Gurusamy Manivannan, CRC Press 2007.
  • Thomas, John G. and Nancy T. Rector .  Susceptibility-Testing Protocols for Antibiograms and Preventive Surveillance: A Continuum of Data Collection , Analysis and Presentation .  p. 105-138. in Antimicrobial Susceptibility Testing Protocols . Ed by Richard Schwalbe, Lynn Steele-Moore and Avery C. Goodwin   CRC Press. 2007  


2006

  • Textbook of Diagnostic Microbiology, 3rd Edition. Mahon, C.R., Lehman, D.C. and Manuselius, G. Eds. “Biofilms: Architects of Disease.” Chapter 31.  2007.
  • Thomas, J., Nakaishi, L., Corum, L. “Antimicrobial Anti-infective Coated Medical Devices: Costs and Consequences of Biofilms” in “Disinfection and Decontamination: Principles, Applications, and Related Issues. CRC Press. 2007.
  • Thomas, J. and Nakaishi, L. Managing the Complexity of a Dynamic Biofilm (Article in Importance of Antiseptic Mouthrinses in the Daily Oral Care Regimen Supplement).  JADA . November 2006.
  •  Livengood, R. and Thomas, J. A Unique Fungal Infection requiring Mold MIC’s. Clinical Microbiology Newsletter. 2006.
  • Thomas, J.  2007 The Year 2006 for Microbiology: Changing Paradigms.  ADVANCE for Administrators in Laboratory.  
  • Thomas, J., Gray, D., Nakaishi, L., Crout, R., McNeil, D., Weyant, R., Marazita, M.  3 Species Oral Microbial Signature from two Rural Populations.  IADR 2006 Orlando.
  • Thomas, J.G., Carpenter, J., Martens, P., Gray, D., and Nakaishi, L. Imaging luminal location of the ETT accretions by CT Topographical radiography.  ICACC 2006 San Francisco
  • Thomas, J.G.,  Martens, P., Gray, D., Nakaishi, L., and Ortiz, M. Impact of ETT accretions on airway resistance in mechanically ventilated patients.  ICACC 2006 San Francisco.
  • Thomas, J., Sokos, LG., Canfield, P., Gray, D. Linking Adverse Outcome of Fungemic Patient to Organism Resistant Phenotype: BEC50 : MIC. ASM 2006 Orlando
  • Thomas, J., Martens, P., Gray, D., Nakaishi, L, Thomas, K. The Impact of Silver Ions Upon Oral/Dental flora Co-Biofilm Colonization in Endotrach (ETT) ASM 2006 Orlando

2005

  • Thomas, J., Lynton, I., Rinde, H. Economic Impact of Biofilms on Treatment Costs. Biofilm Infec Antimicrob Therapy. 2005;21-37
  • Ramadan, H., Sanclement, J., Thomas, J. Chronic Rhinosinusitis and Biofilms.  Otolaryngology Head Neck Surg 2005;132:414-7.
  • Thomas, J. Biofilms. APIC Epidemiology. 2005;96:1-13.
  • Thomas, J., Parsons, J., and Canfield, P. 2005 The Changing Culture in Infectious Disease. ADVANCE Magazine for Administrators of the Laboratory. 6.
  • Thomas, J. 2005. Anaerobic Infections. ADVANCE Magazine for Administrators of the Laboratory 9.
  • Thomas, J. 2005 Antibiotic Resistance and the Clinical Laboratory. ADVANCE Magazine for Administrators. 4.
  • Sessa, A., Shelton, J., Thomas, J., Ceri, H.  Antibiotic Effect on an Engineered Periodontal Biofilm Tooth Surface.  IADR 2005 Baltimore.
  • Thomas, K., Thomas, J., Thomas, K., Schwegler-Berry, D.  Anti-biofilm Effect on Chemically Modified Tetracyclines in an Oral Model.  IADR 2005 Baltimore
  • Thomas, J., Gagisetty, S., Karakiozis, J., Martens, P.  The Antibiofilm Effect of a Silver Releasing Compound in a Polymicrobic Ventilator Endotrach Lung Model.  ASM 2005 Atlanta.
  • Thomas, J., Thomas, K., Powala, C.  Unmasking the Link Between Ventilator Associated Pneumonia (VAP), Periodontal Disease and Biofilms.  ASM 2005 Atlanta.

2004

  • “Biofilms and Implant Infections”, in Medical Biofilms, Sr. Editors, M. Ghonnoum, Case Western Reserve Medical Center and George A. O’Toole, Dartmouth Medical School, ASM Press. 2004.
  • “Economic Impact of Biofilms on Treatment Costs” in Biofilm Infections, Roles of Antibiotic Tolerance and Resistance, Ed., John L. Pace, Marcel-Dekkar Press. 2004.
  • Computerized Antimicrobial Decision Support:  An Offline Evaluation of a Database-Driven Empiric Antimicrobial Guidance Program in Hospitalized Patients with a Bloodstream Infection. Charles Mullett, John Thomas, et al.  IJMI, In Press. 2004.

2003

  • Database-Driven Computerized Antibiotic Decision Support: Novel use of Expert Antibiotic Susceptibility Rules Embedded in a Pathogen-Antibiotic Logic Matrix, Charles J. Mullett, M.D., Ph.D. and John G. Thomas, Ph.D., AMIA Paper 2003.
  • 61 Year Old Immunocompromised Man with a Cough and Worsening Dyspnea, Authors: P. Hartel, D. Taniguchi, J. Thomas, Clinical Micro Newsletter, 25(7):53-55, 2003.
  • ‘“Biofilms and Implant Infections”, in Medical Biofilms, Sr. Editors, M. Ghonnoum, Case Western Reserve Medical Center and George A. O’Toole, Dartmouth Medical School, ASM Press. 2003.
  • Thomas, JG.  2003 The expanding role of microbiology.  ADVANCE for Administrators of the Laboratory 11(12):33-38.
  • Thomas, J.G., Orr, B., 2003 Cost-benefit analysis in Microbiology. ADVANCE Magazine for the Laboratory Administrator 12(15):34-40.
  • Thomas, J.G., 2003 Changing Cultures of Microbiology. ADVANCE Magazine for the Laboratory Administrator 12(12).

2002

  • Christina Debias, Dental Microbiology.  2002.
  • R. Skidmore, Kovach, R., Walker, C., Thomas, J., Bradshaw, M., Leyden, J.,  Powala, C.  “Effects of Subantimicrobial Dose Doxycycline Hyclate and the Treatment of Moderate Acne”, Journal of Dermatology. 2002.
  • Thomas, J.G. 2002. The Re-evaluation of Diagnostic Microbiology, ADVANCE Magazine for the Laboratory Administrator 1:35-38
  • Thomas, J.G. 2002. Development of a Molecular Genetics Test Menu for Microbiology, ADVANCE Magazine for the Laboratory Administrator, 9:9-10.
  • Thomas, J.G. 2002. Changing Paradigms in Microbiology: A Changing Future, ADVANCE Magazine for the Laboratory Administrator, 12.
  • J. Thomas, K. Miller, J. Karakiozis, D. Mayfield, Utilization of Microbiology Database for Implementing a Cost-Effective, Restrictive Strategy for UTIs.    ASM, Salt Lake 2002.
  • J. Thomas, J. Karakiozis, B. Arguero, J. Bergstein, S. Kincaid, P. Kite, Correlation of Endotrach Microbial Biofilm Staging with Organism Morphotype in Critical Care Patients.  ASM, Salt Lake 2002.
  • J. Thomas, A. Murray, J. Karakiozis, K. Thomas, R. Crout and G. Hobbs.  Selection of Emperic Antibiotics vs. Antibiotic Resistance from Periodontal Cultures.  AAP, San Diego 2002.

Selected Invited Presentations

2006

  • Dentsply Endodontics Seminar. Keynote Speaker. Oral Biofilms Links to Disease: Head to Toe. Steamboat, CO. February 4, 2006.
  • Bio-Meriux-ASM. Measuring Microbiology’s Value in a Pay-4-Performance Environment.  Orlando, FL. May 2006.
  • American Society for Clinical Laboratory Science Annual Meeting. Biofilms: Architects of Chronic Diseases.  Chicago, IL. July 2006.
  • American Society for Clinical Laboratory Science. Clinical Rounding—How we make it work in Microbiology.  Chicago, IL. July 2006.
  • Allegheny General Hospital.  Biofilm Scandals in the Ventilated Patient: Links to Pulmonary Infections via Up-Regulation. Pittsburgh, PA. August 2006.
  • Virginia Dental Society.  Oral Biofilms Links to Diseases-Head to Toe.  Roanoke, VA.  September 2006.
  • American Institute of Oral Biology.  Biofilm Scandals in the Oral Cavity. Palm Springs, CA.  October 2006.
  • American Institute of Oral Biology (AIOB).  Links to Systemic Infections: Head to Toe.  Palm Springs, CA.  October 2006.
  • Asia Pacific Educational Tour.  Biofilms: Oral and Systemic Diseases
    • Thai Periodontal Society. Plaque Biofilm and Oral Health. Bangkok, Thailand. April 5, 2006.
    • Thai Society for Public Health Dentistry. Relationship of Oral Health to General Health—Myth or Truth AND Prevention of Periodontal Diseases in ANC Clinic. Bangkok, Thailand. April 5, 2006.
    • International Dental Exhibition and Meeting (IDEM) Symposium on Minimal Intervention. Oral Biofilms: Architects of Disease, Head to Toe. Singapore. April 7. 2006.
    • Global Expert Panel Meeting. Mouthrinses: Impact on Oral Health. Singapore. April 8, 2006.
    • National University of Singapore Faculty of Dentistry Lecture. Changing Paradigms in Oral Microbiology: Its Growing Significance in Systemic Diseases. Singapore. April 10, 2006.
    • University of Hong Kong. Biofilm Management and Control AND Strategies for Combating the Bacterial Plaque Biofilm. Hong Kong. April 11, 2006.
    • Malaysia Dental Association Lecture. Oral Biofilms: Architects of Disease, Head to Toe AND Mouthrinses: Impact on Oral Health. Kula Lumpur, Malaysia. Thursday, April 13, 2006.
    • FDI World Dental Federation Lectures. Biofilm and Oral Diseases AND Strategies for Combating the Bacterial Plaque Biofilm AND Biofilms and Implants. Taichung, Taiwan. April 15, 2006.
    • Peking University School of Dentistry lecture.  Strategies for Combating the Bacterial Plaque Biofilm. Beijing, China. April 17, 2006.
  • Pfizer Round Table. Biofilm Scandals in the Oral Cavity: Architects of Disease.  London, England July 2006.

2005

  • Clinical Microbiology Society of Japan, National Meeting. The Significance of Blood Cultures: Today and Tomorrow. Kyoto, Japan. February 2005.
  • Critical Care Medicine Sponsored Symposium. “Ventilator Associated Pneumonia.”  Cancun, Mexico. March 2005.
  • American Society of Microbiology. BioMeriux. “Biofilms: Architecture of Disease.” Atlanta, Georgia. June 2005.
  • Mexican Society o Infectious Disease. “Biofilms: Hall-mark of Chronic Infections.” Cancun, Mexico. July  2005.
  • CDC Sponsored Regional Meeting: IDEAS Conference. “Significance of Biofilms to I.C.U.” Harrisburg, Pennsylvania. October 2005.
  • University Symposium in Clinical Laboratory Science.  New Jersey School of Medicine and Dentistry. Microbiology Gone Wild. 2005.  “Biofilms—What Every Clinical Microbiologist Needs to Know.”  “Assessment/Outcomes: Proving Your Worth.”  Pitscataway, New Jersey. October 2005
  • Keynote Speaker of Regional ASM Meeting Allegheny Branch.  Waksman Foundation for Microbiology Lectures.  Lock Haven University. “Biofilms and Microbiology.”  Clearfield Campus, Clearfield, Pennsylvania.  November 2005.
  • University of North Carolina. “Antibiotics and Custodial Use.” Chapel Hill, NC.  December 2005.

2004

  • American Society for Micobiology.  Keynote Presentation for Vitek BioMerieux, “First to Know, Integrating Outcomes and Diagnostic Microbiology: Is there a Future?” New Orleans, LA.  2004.
  • Annual Meeting of West Virginia Respiratory Therapists Biofilms and Ventilator Associated Pneumonia: What is the Connection? Charleston, WV.  2004.
  • South Central Association of Clinical Microbiology (SCACM), Biofilms and the Practicing Clinical Microbiologists, What are the Consequences? Columbus, OH, 2004.

2003

  • The 3 Rivers Association of Practitioners of Infection Control, Pittsburgh Branch Medical.  “Consequences in Impact on Decision Making for Infection Control: Biofilms.”  Pittsburgh, PA.  2003.
  • Allegheny General Hospital, Department of Pathology .Clinical Microbiology and Impact on Decision Making in the 2000’s.  Pittsburgh, PA. 2003.
  • American Society for Microbiology Workshop, Biofilms III, Washington, D.C. 2003.
  • Symposium CLMA. Outcomes as a Management Tool for Survival in the 2000’s. Salt Lake City, UT. 2003.
  • Stanford University, Department of Infectious Diseases and Critical Care Biofilms and Emerging Resistance: An Oxymoron.  2003.
  • University of Pittsburgh Medical Center. , Division of Pulmonary Care, Infectious Diseases and Respiratory Therapy, The Significance of Biofilms in Respiratory Therapy, (sponsored by Chiron). 2003.

2002

  • Sigma Uldridge Diagnostics.  Regional 16 Eastern States Teleconference. Utilization of an Outcomes Model to Assess the Impact of Diagnostic Protocols for Pulmonary Embolism.  2002.
  • One-Day Workshop.  Sigma Diagnostics.  Be a Believer: the Use of an Outcomes Model to Assess Impact of Diagnostic Protocols for Venous Thrombosis.  Supported by Sigma Uldridge. Durham, NC. 2002.
  • The West Virginia Osteopathic Society Semi-Annual Meeting Update on Mechanisms of Infections and Antibiotic Resistance: Where Have You Been?  Charleston, WV.  2002.
  • University of Calgary.  Guest of Howard Ceri, Professor, Department of Microbiology, Section of Biofilms. Calgary, Canada. 2002.
  • University of Calgary Medical Center Hospital.  Unmasking the Clinical Significance of Biofilms in Lumenal Analysis of Catheters and Endotrachs.  Calgary, Canada.  Sponsored by the University of Calgary Biofilm Group, Howard Ceri, Ph.D. 2002.
  • International Meeting of Biofilm Symposium.  “Utilization of an Endotrach Model to Describe the Biofilm Lumenal Architecture Influence of Stress Forces.” Lake Louise, Canada.  Sponsored by the University of Calgary. 2002.
  • International Biofilm Symposium, Keynote Speaker.  “Biofilms in ventilator associated pneumonia and endotrach colonization.”  Lake Louise, Canada.  2002.
  • American Society for Microbiology Annual Meeting, Salt Lake City. “Medical Biofilms and Rapid Detection - Part   I”. 2002.
  • Keynote symposium.  Biofilms and diagnostic microbiology: an Oxymoron.  Convener and primary speaker.  2002.
  • American Society for Microbiology Annual Meeting.  Workshop Convener and Presenter.  “Biofilms in Medical Microbiology.” Salt Lake City, UT.
  • ASCP Workshop, Minneapolis, MN.  Two-day.  Antibiotic Resistance, Laboratory Detection and Reporting. 2002.
  • Southcentral Association of Clinical Microbiology (SCACM) Regional Meetings.  “The Future of Microbiology and Consequences of Biofilms for Laboratory Detection.” Chicago, IL. October 2002.
  • 93rd Annual West Virginia School of Dentistry, West Virginia Meeting,  2 hour symposium, Oral/Dental Microbiology, the Growing Importance of Periodontal Pathogens.  Greenbrier, WV.  2002.