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| Department of Physiology and Pharmacology David G. Frazer Adjunct Associate Professor of Physiology and Mechanical Engineering Ph.D., Electrical Engineering, The Pennsylvania State University, 1970 Ph.D., Physiology and Biophysics, West Virginia University, 1974 Phone: 304-285-5873 Research Interests Respiration, bioengineering, lung acoustics, laser technology, animal exposure systems. Description of Research The major emphasis of our research has been to examine the mechanical properties of lungs, especially the mechanics of the alveoli and the very small airways. At the present time we are working on projects dealing with: 1) the role of surface forces on liquid menisci formation in the airways which results in premature airway closure, 2) the role of surface forces on the alveolar pores of Kohn during the formation of emphysema, 3) the development of acoustical reflection techniques to measure changes in tracheal cross-section area which are related to the development of asthma, 4) the development of small animal aerosol exposure systems to study the initial stages of occupational lung diseases and 5) the design of video reconstruction techniques to examine the micromechanics of the lung as individual alveoli change volume. Recent Publications Witmoyer T.B., Sneckenberger J.E., Frazer D.G., Robinson W.A., Giza A. and DeLong D.S.: Microcomputer control of particle concentrations in a cotton dust exposure system. Advances in Bioengineering, ASME, pp. 143-146, 1988. Frazer D.G., Robinson V.A., DeLong D.S., Petzonk E.L., Weber K.C. and Jones T.S.: Mechanisms of airflow interruption in guinea pigs exposed to cotton dust. Proc. Twelfth Cotton Dust Res. Conf. R.R. Jacobs and P.J. Wakelyn (eds) National Cotton Council, Memphis, TN, pp. 74-78, 1988. Afshari A.A., Frazer D.G. and Stnaley C.: Correlation of lung crackles with surface deformation using holographic inferometry. Advances in Bioengineering, ASME, pp. 13-15, 1989. |
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