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| Department of Physiology and Pharmacology Stanley D. Yokota Associate Professor of Physiology Ph.D., University of California at Riverside, 1979 Postdoctoral Fellowship, University of Arizona Phone: 304-293-1492 Email: syokota@hsc.wvu.edu Research Interests Renal physiology, microcirculatory physiology, transport, osmoregulation Description of Research Current interests in this laboratory are centered on the regulation of glomerular filtration and renal blood flow in vertebrate kidneys, and the mechanistic determinants of glomerular filtration at the level of the individual glomerulus. The approach to these problems involves whole animal and isolated organ methods, as well as techniques for the study of isolated arterioles and individual glomeruli. Intravital epifluorescence video microscopy combined with micropuncture techniques are utilized to assess the microvascular dynamics of individual glomeruli in real-time. A modified Burg in vitro microperfusion method is utilized to study the function of isolated renal microvessels and isolated intact glomerular complexes under controlled conditions. Other interests include the regulation of salt and water homeostasis in vertebrates, and the function of specialized excretory organs. Recent Publications Yokota S.D.: Ophidian kidney preparation for the measurement of glomerular dynamics in real-time. Pfluegers Arch. 415:501-503, 1990. Yokota S.D., and Dantzler W.H.: Measurements of blood flow to individual glomeruli in the ophidian kidney. Am. J. Physiol. 258:R131-R1319, 1990. Yokota S.D.: Glomerular filtration dynamics in reptiles: endocrine effects. In: Progress in Comparative Endocrinology, Wiley-Liss, NY, pp. 565-571, 1990. |
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