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| Research and Graduate Education MBRCC-PFG MARY BABB RANDOLPH CANCER CENTER The MBR Cancer Center and Office of Research and Graduate Education announces the availability of awarding Pilot Funding Grants (PFGs) up to one-year in duration, which are directed by faculty at the level of Assistant Professor or above. Applicants may include faculty from the Schools of Medicine, Dentistry, Nursing, and Pharmacy or other WVU Schools and Colleges. Projects will be relevant to the overall goals of the MBR Cancer Center and its research programs (including and not limited to the following) in basic science – tumor microenvironment and cell signaling networks; clinical/translational science – breast cancer, lung cancer, hematological malignancies and bone marrow transplantation, and developmental therapeutics; and population and prevention science – Translational Tobacco Reduction Research; cancer risk monitoring, including GIS; health services and outcomes research; and prevention research and education including molecular prevention. Deadline for submission of MBRCC-PFG is March 14, 2008 (5:00PM) (Submissions Beyond 5:00 PM on March 14 Cannot be Accepted) Proposals for this PFG solicitation are specifically requested in the following areas:
Pilot Funding Grants (PFGs): PFGs are provided to foster scientific collaborations among the MBRCC faculty and to assist faculty in obtaining extramural grant support for basic, translational/clinical, and population-based and prevention research projects, which are aligned with thematic research areas in the Cancer Center. They are available to faculty who have not yet received significant extramural support; to faculty with existing extramural grant support, who wish to obtain funding for a new research project or receive vital funding to support a revision or competitive renewal of a project. Recipients of MBRCC-PFGs must submit an external grant application to federal agency (e.g., NIH, NSF, DOD, and CDC), voluntary association or foundation (e.g., ACS, Keck Foundation, Susan G. Komen For the Cure), industry, or some other agency including the State of West Virginia, within 6 months after the end of the internal funding period. PFGs are intended to facilitate external research funding and not to provide long-term, internal support for research endeavors. Eligibility: PFGs are available to current members of the MBRCC, HSC and other WVU faculty, both tenure-track and non-tenure track at the level of Assistant Professor or above. If the applicant is not a current member of the MBR Cancer Center, they will be asked to apply for membership within the Cancer Center. A PFG award is contingent upon an investigator being granted membership in the Cancer Center; this is to ensure cancer focus and commitment to cancer research.A faculty member can be a principal investigator on a current BFG or RDG provided the current PFG is cancer focused and is distinctly different from the active BFG or RDG project. A PFG applicant cannot have a project of the same title and equivalent focus currently pending or under review under the BFG or RDG mechanism. Review Criteria: PFGs are reviewed by a committee composed of faculty members with expertise in research and knowledge of external grant review processes. Each application will be scored comparable to the NIH scoring process. To be helpful, brief written critiques organized in the format of NIH study section reviews will be provided to all applicants, regardless of award status. MBRCC Pilot Funding Grants The major criteria for funding are scientific merit of the project aligned with the topical requests for proposals as outlined above for this PFG solicitation (if applicable); likelihood that funding will result in submission of a competitive, extramural grant application [with NCI Cancer Center Support Grant (CCSG) – eligible funding given priority]; clear indication of cancer focus and relevance to scientific thematic areas of research interest in the MBRCC that fosters intra-programmatic and/or inter-programmatic collaborations that result in peer reviewed publication(s) in a timely manner, especially to set stage for a extramural research grant application. Factors that will be evaluated include the significance and innovation of the planned research, strength of the experimental plan (hypothesis-driven given priority), and the research training, expertise and productivity of the principal investigator. Award and Use of the Grants: If an award is made, the investigator will be instructed as to the source(s) of funds to be used and the appropriate acknowledgement of support that should appear in scientific presentations and publications. It is imperative that the investigator comply with this request as often times these funds are derived from a variety of philanthropic efforts that the Development Office and Cancer Center coordinates, and wishes to thank and acknowledge the donors in order to sustain this vital pool of funds. PFGs are awarded for a period of up to one year. Unexpended funds are returned to the MBR Cancer Center at the end of the funding period in order to help other faculty in need. Residual funds must also be returned if the principal investigator plans to leave WVU during the award period. In such an event, the Cancer Center and the Office of Research and Graduate Education must be notified immediately by both the investigator and department chair. Funds can be used to support existing technical personnel, purchase supplies, or purchase and upgrade equipment directly used in the research project. Funds cannot be used to support faculty salaries, stipends for students in the HSC or WVU graduate programs, purchase general office equipment, international travel, or to hire new personnel. Exception: Student stipends and hiring new or funding existing professional support staff are allowable expenses for the population- and prevention-focused applications. Clear justification should be provided for all requested funds. Maximum Grant to be Awarded: $50,000 per grant. For tobacco research related projects the maximum award is $25,000. NOTE: For this solicitation 3 awards at the $50,000 level and two at the $25,000 level will be made. If applications are NOT meritorious all awards will not be made; targeted score should be 199 or better. Application Process: Applications and support material(s) should be submitted by the close of business (5:00 pm) on the deadline date to the Office of Research and Graduate Education, 2267 Health Sciences South (to Barbara Allen, ballen@hsc.wvu.edu). MBRCC Pilot Funding Grant The following should be submitted: 1) Completed online application form Submit the following to Barbara Allen (electronically if possible). If support material is sent by post, please make 5 copies of the submitted material.2) Research Plan in NIH format (limited to five single-spaced pages) should include: a. Specific Aims: Outline the goals of the project, the hypotheses to be tested, and the key aspects of the experimental plan.3) Biosketch submitted electronically in NIH format, limited to three pages. 4) Copies of IRB approval (if applicable) – including compliance with HIPPA regulations and human subject training certification, IACUC, and IBC approvals via email or postal services. If approval has not been obtained, provide evidence that protocols have been submitted to the relevant institutional review committees. 5) If the present application is a revision of a previously submitted but unfunded RDG or BFG (there must be demonstrable cancer focus in the original application), provide a letter detailing how the new proposal addresses the concerns raised in the prior review. 6) Budget and budget justification. Application Form Please Note: Completion of this application is only the first step in the application process. You will need to email or send by post the items listed above. All parts of the application must be received before the due date listed above. Review Process The MBRCC Pilot Funding Grant Committee Chairs are to be named. Each grant application is assigned to a primary reviewer, a secondary reviewer, and a reader each of whom provides a written critique following the general NIH review format, as follows. These written critiques are provided to the applicant. This Critique is comprised of the following elements:
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