Patrick S. Callery, Ph.D. Professor of Pharmaceutical Sciences Chair, Department of Basic Pharmaceutical Sciences Department of Basic Pharmaceutical Sciences West Virginia University P.O. Box 9530 Morgantown, WV 26506-9530 Phone: (304) 293-1482 Fax: (304) 293-2576 E-Mail: pcallery@hsc.wvu.edu

Education:

Post-doctoral Training - University of Maryland Baltimore
Graduate Training - Ph.D., Pharmaceutical Chemistry, University of California San Francisco
Undergraduate Training - B.S., Pharmacy, University of Utah

Research Interests:

Drug Design, Drug Metabolism, Mass Spectrometry.

Recent Publications:

Tirumalai P, Gannett PM, Callery PS, Bland TM, Tracy TS, Conversion of methamphetamine to N-methyl-methamphetamine in formalin solutions. J Anal Toxicol. 2005;29:48-53.

Shakleya, DM, Tarr SG, Kraner JC, Clay DJ, Callery PS, Potential marker for smoked methamphetamine hydrochloride based on a gas chromatography-mass spectrometry quantification method for trans-phenylpropene. J Anal Toxicol. 2005;29:552-5.

Bland TM, Haining RL, Tracy TS, Callery PS, CYP2C-catalyzed delta9-tetrahydrocannabinol metabolism: kinetics, pharmacogenetics and interaction with phenytoin. Biochem Pharmacol. 2005;70:1096-103.

Shakleya DM, Kraner JC, Kaplan JA, Callery PS, Methylation of 3,4-methylenedioxyamphetamine (ecstasy, MDMA) in formalin-fixed human liver tissue, J Anal Tox. 2005;29:715-717.

Myers AL, Williams HE, Kraner JC, Callery PS, Identification of anhydroecgonine ethyl ester in the urine of a drug overdose victim. J. Forensic Sci. 2005;50:1481-5.

Sanga M, Younis IR, Tirumalai PS, Bland TM, Banaszewska M, Konat GW, Tracy TS, Gannett PM, Callery PS, Epoxidation of the methamphetamine pyrolysis product, trans-phenylpropene, to trans-phenylpropylene oxide by CYP450 enzymes and stereoselective glutathione adduct formation. Toxicol Appl Pharmacol. 2006;211:148-156.

Shakleya DM, Kraner JC, Kaplan JA, Callery PS, Multistage mass spectrometric method for methamphetamine methylation in formalin fixed liver tissue, Forensic Sci Int. 2006 [Epub ahead of print]

Patents:

M.D. Loberg, P.S. Callery, and M. Cooper, New Pharmaceutical Chelates and Methods of External Imaging. U.S. Patent 4,017,596, 1977, plus foreign patents. Marketed in U.S. by New England Nuclear and Squibb and in Canada by Merck Frosst.

P.S. Callery, J. Wright, N. Zenker, and C.S. Stone, Antihypertensive Benzoxazolones. U.S. Patent 4,034,100, 1977, plus foreign patents. Assigned to Merck and Co.

P.S. Callery, M.J. Egorin, Y. Li, and Z.-M. Yuan, Diaziridinylpolyamine Anti-Cancer Agents. U.S. Patent 5,612,329, 1997.

P.S. Callery, J. Wright, and N. Zenker, Antihypertensive Benzimidazolones. U.S. Patent 4,073,929, 1977, plus foreign patents. Assigned to Merck and Co.

Positions:

Assistant Professor, University of Maryland Baltimore, 1974-1978
Associate Professor, University of Maryland Baltimore, 1978-1990
Professor, University of Maryland Baltimore, 1990-1997
Adjunct Professor of Chemistry, Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1993-
Professor and Chair, Department of Basic Pharmaceutical Sciences, and Assistant Dean for Research and Graduate Programs, School of Pharmacy, West Virginia University, 1997-