Department of Basic Pharmaceutical Sciences
West Virginia University
Morgantown, WV 26506-9530

Phone: (304) 285-6372

 E-Mail: jbower@cdc.gov

Research Advisor:  Dr. Xianglin Shi

Education: 

 

May 2001 B.S. in Biological Sciences

University of Notre Dame

South Bend, IN

 

 

 

Research Interests:

 

 Molecular mechanisms of metal-induced carcinogenesis.

 

Publications:

Bower, J., and Shi, X. Environmental Health Research in the Post-Genomic Sequencing Era: New Fields, New Challenges, and New Opportunities. (submitted)

Leonard, S.S., Bower, J.J., and Shi, X. Conference overview: Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses. Mol Cell Biochem (in press)

Chen, F., Zhang, Z., Bower, J., Lu, Y., Leonard, S.S., Ding, M., Castranova, V., Piwnica-Worms, H., and Shi, X. "Arsenite-Induced Cdc25C Degradation is through the KEN-box and Ubiquitin-Proteasome Pathway." (2002) Proc Natl Acad Sci 99:1990-5

Chen, F., Bower, J., Leonard, S.S., Ding, M., Lu, Y., Rojanasakul, Y., Kung, H.H., Vallyathan, V., Castranova, V., and Shi, X. "Protective Roles of NF-kappa B for Chromium(VI)-induced Cytotoxicity Is Revealed by Expression of I?B Kinase-beta Mutant." (2002) J Biol Chem 277:3342-3349.

Chen, F., Bower, J., Demers, L.M., and Shi, X. "Tranduction of NF-kB Activation" (2001) Atlas Genet Cytogenet Oncol Haematol. (December)

Bohlson, S. S., Strasser, J.A., Bower, J.J., and Schorey, J.S. "Role of Complement in Mycobacterium avium Pathogenesis: In Vivo and In Vitro Analyses of the Host Response to Infection in the Absence of Complement Component C3" (2001) Infect Immun 69:7729-7735.