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Study evaluates gene variations known to be involved in drug abuse and associated treatment outcomes with treatment in the COAT program


Evaluating gene variations implicated in opioid abuse treatment and outcomes

School, Department, or Center

School of Medicine, Department of Behavioral Medicine & Psychiatry


Vincent Setola, PhD Laura Lander, MSW, LICSW


The goal of this study is to test whether heritable single-nucleotide polymorphisms (SNPs), known to be involved in drug abuse and/or predisposing behaviors, are associated with treatment outcome at the Chestnut Ridge Comprehensive Opioid Addiction Treatment (COAT) clinic. A major expected outcome of the proposed pilot is that we will establish a routine protocol for genotyping patients in the COAT clinic. Another anticipated outcome is that we will identify SNPs that are predictive of treatment success or failure. The proposed research will enable us, using facile, non-invasive genotyping technology, to identify COAT clinic patients who are more likely to succeed or fail, enabling personalized treatment strategies.

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