Study evaluates treatment outcomes among patients on Buprenorphine/Naloxone receiving mindfulness intervention plus treatment as usual vs. treatment as usual only
An evaluation of treatment outcomes among patients with Opioid Use Disorders on Buprenorphine/Naloxone receiving mindfulness intervention plus TAU vs. TAU only.
School, Department, or Center
School of Public Health, Department of Behavioral Medicine & Pyschiatry
Laura lander, MSW Keith Zullig, PhD
This study combines the two interventions of medication management with buprenorphine for the treatment of opioid use disorder with mindfulness-based relapse prevention. Outcomes measured are craving for drugs, treatment retention, relapse rates, symptoms of anxiety and depression, and structural brain changes. Patients who are currently enrolled in treatment for opioid use disorder at Chestnut Ridge Center in the Comprehensive Opioid Addiction Treatment (COAT) program are being asked to participate in the study. The targeted patients are those who are stable in early recovery with 90-245 days clean, being treated in the intermediate stage of treatment. Treatment as usual (TAU) in the intermediate stage of treatment in the COAT program consists of every other week medication management, every other week group therapy and required attendance at 4 AA or NA meetings every week. The non-interventional portion of the study will take place first during which participants will attend 8 weeks of TAU, have pre and post Magnetic Resonance Imaging (MRI) and be monitored every other week for retention, relapse, craving as a well as symptoms of anxiety and depression. The mindfulness portion of the study take place second and will include attending weekly meetings designed to teach mindfulness techniques and relating this to depression, anxiety, and craving. These weekly sessions will last 60-90 minutes over 8 weeks and include home mindfulness exercises. During the 8 weeks that participants take part in the mindfulness group they will be excused from attending one of their AA/NA meetings per week. Retention, relapse, craving as a well as symptoms of anxiety and depression will be monitored every other week and a final MRI will be conducted at the conclusion of the mindfulness intervention stage.
Monongalia Counties and surrounding areas« Back to Research Initiatives