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Study searches for genetic markers to enhance the treatment of pregnant women with opioid use disorder and their neonates

Program

Using a whole exome sequencing approach to enhance the treatment of pregnant women with opioid use disorder and their neonates.

School, Department, or Center

School of Medicine, Department of Behavioral Medicine & Psychiatry

Contact

Laura Lander, MSW

Description

In this study, we will conduct a search for genetic markers in mothers and in their babies that are predictive of the clinical outcomes for babies with NAS. We will also explore what evidence-based protocols are most effective for the treatment of NAS. This project has two distinct but related aims.
Aim 1: Determine the genetic profiles from mother-baby dyads for women active in medication-assisted treatment programs whose babies are at risk for developing NAS.
Aim 2: Explore the most effective protocols for the treatment of NAS, with specific attention to medication used, mothers’ substance use treatment outcomes and the role of breastfeeding.

Area Served

Statewide

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