Associate Professor

Graduate Training: University of Kentucky
Fellowships: University of Illinois | Beth Israel Deaconess Medical Center /Harvard Medical School

Department of Physiology & Pharmacology
West Virginia University School of Medicine
One Medical Center Drive
P.O. Box 9229 Health Sciences Center
Morgantown, WV 26506-9229
t: 304-293-1502
f: 304-293-3850
e: shileman@hsc.wvu.edu

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Research Interests

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The goal of our research is to define the neurobiological pathways controlling food intake and obesity in the female and how those pathways are integrated into a system whereby nutrition can influence body weight and/or fertility.  To accomplish this goal, several surgical, endocrine and molecular biology techniques are employed, including radioimmunoassay, in situ hybridization histochemistry, immunocytochemistry, neuroanatomical tract tracing and RT-PCR, with both rodents and sheep being used as models.  The work is focused on the neural mechanisms whereby certain circulating metabolic signals, such as leptin, insulin and IGF-1 may regulate food intake and reproduction as well as examining potential sex-dependent differences in these systems.