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Publications

  1. Evaluation of Bioenergetic Function in Cerebral Vascular Endothelial Cells. Rellick SL, Hu H, Simpkins JW, Ren X. J Vis Exp. 2016 Nov 19;(117). doi: 10.3791/54847. PMID: 27911398
  2. Deciphering the Blood-Brain Barrier Damage in Stroke: Mitochondrial Mechanism. Ren X, Simpkins JW. J Neuroinfect Dis. 2015 Oct;6(Suppl 2). pii: e002. No abstract available. PMID: 27213159
  3. Geissoschizine methyl ether protects oxidative stress-mediated cytotoxicity in neurons through the 'Neuronal Warburg Effect'. Sun J, Ren X, Qi W, Yuan D, Simpkins JW. J Ethnopharmacol. 2016 Jul 1;187:249-58. doi: 10.1016/j.jep.2016.04.034. PMID: 27114061
  4. Impacts of prenatal nanomaterial exposure on male adult Sprague-Dawley rat behavior and cognition. Engler-Chiurazzi EB, Stapleton PA, Stalnaker JJ, Ren X, Hu H, Nurkiewicz TR, McBride CR, Yi J, Engels K, Simpkins JW. J Toxicol Environ Health A. 2016;79(11):447-52. doi: 10.1080/15287394.2016.1164101. PMID: 27092594
  5. Tert-butylhydroquinone compromises survival in murine experimental stroke. Sun J, Hu H, Ren X, Simpkins JW. Neurotoxicol Teratol. 2016 Mar-Apr;54:15-21. doi: 10.1016/j.ntt.2016.01.004. PMID: 26827673
  6. Mitochondrial Impairment in Cerebrovascular Endothelial Cells is Involved in the Correlation between Body Temperature and Stroke Severity. Hu H, Doll DN, Sun J, Lewis SE, Wimsatt JH, Kessler MJ, Simpkins JW, Ren X. Aging Dis. 2016 Jan 2;7(1):14-27. doi: 10.14336/AD.2015.0906. PMID: 26816660
  7. MiR-34a regulates blood-brain barrier permeability and mitochondrial function by targeting cytochrome c. Bukeirat M, Sarkar SN, Hu H, Quintana DD, Simpkins JW, Ren X. J Cereb Blood Flow Metab. 2016 Feb;36(2):387-92. doi: 10.1177/0271678X15606147. PMID: 26661155
  8. Lipopolysaccharide exacerbates infarct size and results in worsened post-stroke behavioral outcomes. Doll DN, Engler-Chiurazzi EB, Lewis SE, Hu H, Kerr AE, Ren X, Simpkins JW. Behav Brain Funct. 2015 Oct 13;11(1):32. doi: 10.1186/s12993-015-0077-5. PMID: 26463864
  9. Sequential Upregulation of Superoxide Dismutase 2 and Heme Oxygenase 1 by tert-Butylhydroquinone Protects Mitochondria during Oxidative Stress. Sun J, Ren X, Simpkins JW. Mol Pharmacol. 2015 Sep;88(3):437-49. doi: 10.1124/mol.115.098269. PMID: 26082377
  10. Mitochondrial crisis in cerebrovascular endothelial cells opens the blood-brain barrier. Doll DN, Hu H, Sun J, Lewis SE, Simpkins JW, Ren X. Stroke. 2015 Jun;46(6):1681-9. doi: 10.1161/STROKEAHA.115.009099. PMID: 25922503
  11. Rapid mitochondrial dysfunction mediates TNF-alpha-induced neurotoxicity. Doll DN, Rellick SL, Barr TL, Ren X, Simpkins JW. J Neurochem. 2015 Feb;132(4):443-51. doi: 10.1111/jnc.13008. PMID: 25492727