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Andrey Bobko, Ph.D.

   Andrey Bobko received a Bachelor degree in Ecology in Novosibirsk State University (Novosibirsk, Russia) following with Master Degree in Physical chemistry in the same university. Several years later he has finished his PhD thesis in the field of Physical Chemistry in Institute of Chemical Kinetics and Combustion (Novosibirsk, Russia). A. Bobko received his post-doctoral training in Dorothy M. Davis Heart and lung Research Institute at the Ohio State University (Columbus, USA) in the field of in vivo Electron Paramagnetic Resonance Spectroscopy and Imaging, later  he was appointed as Research Assistant Professor in Biochemistry Department in Health Science Center in West Virginia University (Morgantown, USA).

The sphere of interest:

   Magnetic resonance imaging and spectroscopy of living systems (including Electron Paramagnetic and Nuclear Magnetic Resonance techniques); development of multifunctional paramagnetic probes and approaches for measurement/detection of reactive oxygen/nitrogen species and various physiologically important analytes (pH, pO2, inorganic phosphate, glucose, glutathione et cet.) in in vivo systems; study of mechanism and kinetics of reaction between short-lived intermediates with probes.

Selected publications:

- Bobko, AA; Kirilyuk, IA; Grigor'ev, IA; Zweier, JL; Khramtsov, VV. Reversible reduction of nitroxides to hydroxylamines: Roles for ascorbate and glutathione. Free Radical Biology & Medicine 2007; 42(3): 404-412. PMCID: PMC1829321.

- Bobko, AA; Dhimitruka, I; Zweier, JL; Khramtsov, VV. Fourier Transform EPR Spectroscopy of Trityl Radicals for Multifunctional Assessment of Chemical Microenvironment. Angewandte Chemie International Edition 2014, 53(10), 2735-2738. PMCID: PMC3985337.

- Bobko, AA; Eubank, TD; Voorhees, JL; Efimova, OV; Kirilyuk, IA; Petryakov, S; Trofimiov, DG; Marsh, b; Zweier, JL; Grigor'ev, IA; Samouilov, A; Khramtsov, VV. In vivo monitoring of pH, redox status, and glutathione using L-band EPR for assessment of therapeutic effectiveness in solid tumors. Magnetic Resonance in Medicine 2012, 67(6), 1827-1836. PMCID: PMC3305854.

- Bobko, AA; Dhimitruka, I; Zweier, JL; Khramtsov, VV. Trityl radicals as persistent dual function pH and oxygen probes for in vivo electron paramagnetic resonance spectroscopy and imaging: concept and experiment. Journal of the American Chemical Society 2007, 129 (23), 7240-7241.

- Bobko, AA; Khramtsov, VV. Mechanistic studies of oxidative decomposition of Angeli's salt and PAPA NONOate. Nitric Oxide: Biology and Chemistry, 40, 92-98.