Martin Poncelet, M.Sci.
Martin holds a master degree from the Université catholique de Louvain (Belgium) in chemistry. After graduation he moved to industry where he acquired expertise in immunoassays for medical diagnosis. After eight years of industrial experience, Martin moved back to academia in 2016 to join the IMMR center at West Virginia University. He is currently working with Dr. Driesschaert on the development of paramagnetic probes for biomedical Electron Paramagnetic Resonance.
The sphere of interest:
His current research is focused on the synthesis and characterization of biocompatible stable triarylmethyl radicals as biophysical tools for biomedical in vivo and in vitro EPR.
Selected publication
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Poncelet M, Driesschaert B. A 13C-Labeled Triarylmethyl Radical as an EPR Spin Probe Highly Sensitive to Molecular Tumbling. Angew Chem Int Ed Engl. 2020 Jun 15. doi: 10.1002/anie.202006591.
Sanzhaeva U, Poncelet M, Tseytlin O, Tseytlin M, Gencheva M, Eubank TD, Khramtsov VV, Driesschaert B. Synthesis, Characterization, and Application of a Highly Hydrophilic Triarylmethyl Radical for Biomedical EPR. J Org Chem. 2020 Aug 21;85(16):10388-10398.
Poncelet M, Huffman JL, Khramtsov VV, Dhimitruka I, Driesschaert B. Synthesis of hydroxyethyl tetrathiatriarylmethyl radicals OX063 and OX071. RSC Adv. 2019;9(60):35073-35076.
Poncelet M, Driesschaert B, Tseytlin O, Tseytlin M, Eubank TD, Khramtsov VV. Dextran-conjugated tetrathiatriarylmethyl radicals as biocompatible spin probes for EPR spectroscopy and imaging. Bioorg. Med. Chem. Lett. 2019; 29(14):1756-1760.