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Publications 2016 -present


  1. Poncelet M, Driesschaert B. A 13C-Labeled Triarylmethyl Radical as an EPR Spin Probe Highly Sensitive to Molecular Tumbling. Angew. Chem. Intern. Edit. 2020, doi: 10.1002/anie.202006591.

  2. Taguchi A, DeVience S, Driesschaert B, Khramtsov VV, Hirata H. 2020, In vitro simultaneous mapping of the partial pressure of oxygen, pH and inorganic phosphate using electron paramagnetic resonance, Analyst, 145 (9), 3236-3244.
  3. Sanzhaeva U, Poncelet M, Tseytlin O, Tseytlin M, Eubank TD, Khramtsov VV, Driesschaert B. 2020, Synthesis, characterization and application of a highly hydrophilic triarylmethyl radical for biomedical EPR, J. Org. Chem. https://doi.org/10.1021/acs.joc.0c00557.
  4. Poncelet M, Huffman, JL, Khramtsov VV, Dhimitruka I, Driesschaert B. 2019, Synthesis of hydroxyethyl tetrathiatriarylmethyl radicals OX063 and OX071, RSC Adv., 9, 35073-35076.
  5. Poncelet M, Driesschaert B, Tseytlin O, Tseytlin M, Eubank TD, Khramtsov VV. 2019, Dextran-conjugated triarylmethyl radicals as biocompatible spin probes for EPR spectroscopy and imaging, Med.Chem.Lett. 29, 1756-1760.
  6. Gorodetskii AA, Eubank TD, Driesschaert B, Poncelet M, Ellise E, Khramtsov VV, Bobko AA. 2019, Multiparametric Overhauser-enhanced magnetic resonance imaging: visualization of interstitial oxygenation, acidosis and inorganic phosphate concentration, Sci Rep. 9 (1), 12093.
  7. Tseytlin O, Guggilapu P, Bobko AA, AlAhmad H, Xu X, Epel B, O’Connell R, Hoblitzell EH, Eubank TD, Khramtsov VV, Driesschaert B, Kazkaz E, Tseytlin M. 2019. Modular Imaging System: Rapid Scan EPR at 800 MHz, Magn. Reson. 305, 94-103.
  8. Sato-Akaba H, Tseytlin M. 2019. Development of an L-band rapid scan EPR digital console, J. Magn. Reson. 304, 42-52.
  9. Gorodetskii AA, Eubank TD, Driesschaert B, Poncelet M, Ellis E, Khramtsov VV, Bobko AA. 2018. Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging: application for oximetry in tumors, J. Magn. Reson., 297, 42-50.
  10. Sanzhaeva U, Xu X, Guggilapu P, Tseytlin M, Khramtsov V, Driesschaert B. 2018. Imaging of Enzyme Activity by Electron Paramagnetic Resonance: Concept and Experiment Using a Paramagnetic Substrate of Alkaline Phosphatase, Angew. Chem. Intern. Edit. 57, 11701-11705. https://vimeo.com/292981331?ref=tw-share
  11. Scheinok S, Leveque P, Sonveaux P, Driesschaert B, Gallez B, 2018, Comparison of different methods for measuring the superoxide radical by EPR spectroscopy in buffer, cell lysates and cells. Free Radic. Res. 52, 1182-1196.
  12. Komarov DA, Ichikawa Y, Yamamoto K, Stewart NJ, Matsumoto S, Yasui H, Kirilyuk IA, Khramtsov VV, Inanami O, Hirata H. 2018, In vivo extracellular pH mapping of tumors using electron paramagnetic resonance. Anal Chem. 90, 13938-13945.
  13. Khramtsov VV. 2018, In vivo molecular EPR-based spectroscopy and imaging of tumor microenvironment and redox using functional paramagnetic probes, Antiox. Redox Signal. 28 (15), 1365-1377.
  14. Kishimoto S, Cherukuri MK, Khramtsov VV, Utsumi H, Lurie DJ. 2018, In vivo Application of Proton Electron Double Resonance Imaging. Antiox. Redox Signal. 28 (15), 1345-1364.
  15. Khramtsov VV. 2018, In Vivo EPR: Radical Concepts for Translation to the Clinical Setting, Antiox. Redox Signal. 28 (15), 1341-1344.
  16. Bobko AA, Eubank TD, Driesschaert B, and Khramtsov VV. 2018, In Vivo EPR Assessment of pH, pO2, Redox Status and Concentrations of Phosphate and Glutathione in Tumor Microenvironment, J. Vis. Exp. (133), e56624, https://www.jove.com/video/56624.
  17. Khramtsov VV., Davies MJ. 2018. Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017), Free Radical Res. 52 (3), 305-306.
  18. Poncelet M, Driesschaert B, Bobko AA & Khramtsov VV. 2018 Triarylmethyl-based biradical as a superoxide probe, Free Radical Research, 52 (3), 373-379.
  19. Tseytlin M, Stolin AV, Guggilapu P, Bobko AA, Khramtsov VV, Tseytlin O, Raylman RR. 2018. A combined positron emission tomography (PET)-electron paramagnetic resonance imaging (EPRI) system: initial evaluation of a prototype scanner, Phys. Med. Biol. 63 (2018) 105010 (7pp).
  20. Bobko AA, Eubank TD, Driesschaert B, Dhimitruka I, Evans J, Mohammad R, Tchekneva EE, Dikov MM and Khramtsov VV. 2017, Interstitial Inorganic Phosphate as a Tumor Microenvironment Marker for Tumor Progression, Sci. Rep., 7, 41233; doi: 10.1038/srep41233 (2017). www.nature.com/articles/srep41233.
  21. Driesschaert B, Bobko AA, Khramtsov VV, Zweier. JL, 2017. Nitro-Triarylmethyl Radical as Dual Oxygen and Superoxide Probe, Cell Biochem. Biophys., 75: 241-246.
  22. Bobko AA, Evans J, Denko NC, and Khramtsov VV. 2017, Concurrent Longitudinal EPR Monitoring of Tissue Oxygenation, Acidosis, and Reducing Capacity in Mouse Xenograft Tumor Models, Cell Biochem. Biophys. 75, 247-253.
  23. Khramtsov VV, Bobko AA, Tseytlin M, and Driesschaert B. 2017, Exchange Phenomena in the Electron Paramagnetic Resonance Spectra of the Nitroxyl and Trityl Radicals: Multifunctional Spectroscopy and Imaging of Local Chemical Microenvironment, Analyt. Chem. 89 (9), 4758–4771.
  24. Kubota H, Komarov DA, Yasui H, Matsumoto S, Inanami O, Kirilyuk IA, Khramtsov VV and Hirata H. 2017, Feasibility of in vivo three‑dimensional T2* mapping using dicarboxy‑PROXYL and CW‑EPR‑based single‑point imaging, Magn Reson Mater Phys, 30:291–298.
  25. Tseytlin, M. 2017. Concept of phase cycling in pulsed magnetic resonance using sinusoidal magnetic field modulation, Z. Phys. Chem. 231, 689-703.
  26. Epel B, Sundramoorthy SV, Krzykawska-Serda M, Maggio MC, Tseytlin M, Eaton GR, Eaton SS, Rosen GM, Kao JPY, Halpern HJ. 2017, Imaging thiol redox status in murine tumors in vivo with rapid-scan electron paramagnetic resonance, J. Magn. Res. 276, 31-36.
  27. Möser J., Lips K, Tseytlin M, Eaton GR, Eaton SS, Schnegg A. 2017. Using rapid-scan EPR to improve the detection limit of quantitative EPR by more than one order of magnitude, J. Magn. Res. 281, 17-25.
  28. Tseytlin, M. 2017. Full cycle rapid scan EPR deconvolution algorithm, J. Magn. Res. 281, 272-278.
  29. Tseytlin M, Epel B, Sundramoorthy S, Tipikin D, Halpern HJ. 2016, Decoupling of excitation and receive coils in pulsed magnetic resonance using sinusoidal magnetic field modulation, J. Magn. Res. 272, 91-99.
  30. Biller JR, Mitchell DG, Tseytlin M, Elajaili H, Rinard G A, Quine RW, Eaton SS, Eaton GR. 2016. Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo. J. Vis. Exp. 115, e54068. https://www.jove.com/video/54068.
  31. Gorodetsky AA, Kirilyuk IA, Khramtsov VV and Komarov DA. 2016, Functional electron paramagnetic resonance imaging of ischemic rat heart: Monitoring of tissue oxygenation and pH, Magn. Reson. Med. 76:350–358.
  32. Driesschaert B, Bobko AA, Eubank TD, Samouilov A, Khramtsov VV, Zweier JL. 2016, Poly-arginine conjugated triarylmethyl radical as intracellular spin label, Bioorg.Med.Chem.Lett. 26 (7), 1742-1744.