- Principal Investigator
Evaluation of Smoking-Associated Genes in Disparate Appalachian Head and Neck Cancer
This research study will provide new information on the mechanisms by which tobacco-induced genetic damage leads to the earlier death of Appalachian individuals harboring oral tumors with the worst clinical outcomes.
The proposal will systematically evaluate specific, novel tobacco-related genes that have not been previously studied for tumor-promoting effects in oral cancer other cancer type, offering new insight into potential druggable targets in Appalachian and other patient populations with high tobacco use and DNA-damaging risk factors.
- Amount Awarded
- Length of grant
- 23 months