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Investigating the novel role of acetylation in cardiac mitochondrial bioenergetics and function in the aging heart

This research seeks to provide a better understanding of the role of cardiac mitochondrial mechanisms in human aging and age related diseases. An unprecedented rate of aging population growth has a tremendous health and economic impact, and new strategies to mitigate the development of age-related diseases are of paramount importance which makes this research study significant as it will address novel insights into the regulatory role of protein acetylation on mitochondrial bioenergetics and cardiac contractile function in aging heart. Identification of new mechanisms and targets holds significant promise for the development of novel therapeutic outcomes for healthy aging.

Amount Awarded
Length of grant
55 months

Faculty Involved