Weekly Research Updates & Guidance

Please check this page regularly for guidance and research updates.

Last updated: 05/20/24

NIH General Announcements and Notices of Special Interest

Continued Extension of Certain Flexibilities for Prospective Basic Experimental Studies with Human Participants

(NOT-OD-24-118)

National Institutes of Health

This notice replaces NOT-OD-22-205. The purpose of this notice is to further extend interim policy flexibilities, regarding registration and results reporting for a subset of NIH-funded research whose primary purpose is basic experimental studies with humans (BESH) submitted in response to designated BESH Notices of Funding Opportunity (NOFOs). These studies, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants, meet both the NIH definition of a clinical trial and also the federal definition of basic research.

Reporting Data Management and Sharing (DMS) Plan Activities in the Research Performance Progress Report (RPPR)

(NOT-OD-24-123)

National Institutes of Health

This Notice informs the extramural research community of planned changes to the Research Performance Progress Report (RPPR) instructions to address the NIH Data Management and Sharing Policy. Upon receiving approval from the Office of Management and Budget (OMB) Office of Information and Regulatory Affairs (OIRA), NIH will issue new DMS RPPR questions that align with the NIH Final Policy on Data Management and Sharing, to include updates on the status of data sharing, repositories and unique identifiers for data that have been shared.

Notice of Information: NIAID to Increase K99, K25, and K01 Salary and Research Support and R00 Years of Support

(NOT-AI-24-038)

National Institute of Allergy and Infectious Diseases

Effective for application due dates on or after June 12, 2024, NIAID will raise the maximum salary and research support provided on NIAID K99 awards through the Parent and MOSAIC notices of funding opportunities (NOFOs) or any reissues of these NOFOs, on NIAID K25 awards through the Parent NOFO or any reissue, and on NIAID K01 awards through the Parent NOFO or any reissue.

Notice of Change in the NIAID K24 Allowable Application Types and Eligibility Requirements

(NOT-AI-24-043)

National Institute of Allergy and Infectious Diseases

Effective for application due dates on or after June 12, 2024, NIAID will no longer accept renewal (Type 2) applications through the following notices of funding opportunities (NOFOs) or any reissues:Midcareer Investigator Award in Patient Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) and Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required).

Additionally, NIAID will not accept applications from full professors. At the time of application, applicants should be mid-career faculty at the Associate Professor level or equivalent.

NIAID T32 Training Grants Maximum Number of Trainee Slots

(NOT-AI-24-052)

National Institute of Allergy and Infectious Diseases

Beginning with applications submitted for receipt dates on or after September 25, 2024, NIAID will limit the total number of predoctoral and/or postdoctoral training slots to a maximum of 8 trainee slots/training grant in any given year for the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) or any reissue of this funding opportunity as an operational accommodation due to budgetary constraints. This is for competing and non-competing T32 grants. Current NIAID T32 grantees with 10 or more than 10 trainee slots/year will need to reduce their number of slots by not reappointing vacated slots until the 8-slot limit is reached and maintained. Furthermore, for competing renewal (T2) applications, the maximum increase in the number of trainee slots from the past non-competing (T5) year will be 2, up to the maximum 8-slot limit.

Updates to NIH Training Grant Applications - Registration Open for June 5, 2024 Webinar

(NOT-OD-24-124)

National Institutes of Health

The NIH Institutional Training Grant Program application is undergoing changes that take effect for submissions due on or after January 25, 2025. Wondering about the implications for your application preparation? If so, make plans to participate in an informative and engaging webinar, hosted by NIH on June 5 at 1:00 p.m. ET.

Webinar: Updates to NIH Training Grant Applications

Date: Wednesday, June 5, 2024

Time: 1:00 – 2:00 p.m. ET

Free virtual event

Registration Required

Notice of NIAID Withdrawal of Participation from PA-23-080 "Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)"

(NOT-AI-24-044)

National Institute of Allergy and Infectious Diseases

The purpose of this Notice is to inform potential applicants that the National Institute of Allergy and Infectious Diseases (NIAID) will withdraw its participation in PA-23-080, "Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)." This withdrawal will be effective as of May 8, 2024

Notice of Change to Update DMS-related Budget Instructions in PAR-23-145 "Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional)"

(NOT-GM-24-031)

National Institute of General Medical Sciences

The purpose of this Notice is to inform applicants to PAR-23-145 “Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional)” of the updated instructions for the R&R Budget form to include information about requesting Data Management and Sharing (DMS) costs. This Notice is applicable for applications submitted on/after October 5, 2023.

Adjustments to NIH and AHRQ Grant Application Due Dates On and Between May 18 and May 21, 2024

(NOT-OD-24-126)

National Institutes of Health

This notice informs the community of NIH and AHRQ application due date adjustments to accommodate scheduled federal system downtime. Grants.gov has a planned production system outage from Saturday, May 18, 2024 at 12:01 AM ET to Tuesday, May 21, 2024 at 6:00 AM ET (see Grants.gov calendar).

In response, NIH and AHRQ due dates that fall on or between May 18 and May 21, 2024 will move to May 22, 2024.

OPEN House webinar for RFA-NS-24-030: NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)

(NOT-NS-24-101)

National Institute of Neurological Disorders and Stroke

OPEN House Webinar for the D-SPAN F99/K00 Award

Graduate students and their mentors are invited to take part in a virtual OPEN House that will provide attendees resources for preparing an application for the NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) (RFA-NS-24-030).

During this meeting, we will provide an overview of the application and scientific review processes. We will also provide resources to prepare your application. There will be an interactive opportunity to ask NIH staff from across neuroscience mission areas questions in breakout rooms.

More information on this event can be found on the NIH Blueprint D-SPAN F99/K00 webpage.

When: July 30, 2024, 1:00 - 2:30pm ET

Where: Zoom, Registration required: https://nih.zoomgov.com/meeting/register/vJItdu6urzkiHXgfkdYP6P3RN58re-UjWOw

Notice of Change to Award Budget for RFA-NS-24-013: Efficacy and Safety of Amyloid-Beta Directed Antibody Therapy in Mild Cognitive Impairment and Dementia with Evidence of Both Amyloid-Beta and Vascular Pathology (U01 - Clinical Trial Required)

(NOT-NS-24-082)

National Institute of Neurological Disorders and Stroke

The purpose of this Notice is to inform applicants of changes in funds available, award budget, and receipt date for RFA-NS-24-013. Specifically, these changes are made to clarify that NIH intends to commit funds starting in FY25, rather than FY24, and to state that the award budget is capped $46.9M Direct Costs (excluding Consortium F&A) over the 7-year project period, rather than $6.7M each year. The receipt date is being extended until June 14, 2024.

Notice of Change: Early Expiration of NOT-NS-22-095: HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery

(NOT-NS-24-100)

National Institute of Neurological Disorders and Stroke

The purpose of this Notice is to inform the extramural community that NOT-NS-22-095: "HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery", will be expired as of October 22, 2024.

Notice of Intent to Publish a Funding Opportunity Announcement for RNA Modifications Driving Oncogenesis (RNAMoDO; U01 Clinical Trial Not Allowed)

(NOT-CA-24-053)

National Cancer Institute

The National Cancer Institute (NCI) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the RNA Modifications Driving Oncogenesis (RNAMoDO) Initiative. It aims to promote mechanistic research in the emerging area of RNA modifications that drive oncogenesis, with a focus on the central role of RNA modifications in translational reprogramming of cancer cells.

NSF – National Science Foundation General Announcements

Division of Biological Infrastructure (DBI) Virtual Office Hours

Tuesday, May 21, 2024, 3:00 p.m. – 4:00 p.m.

Representatives from across the division will be available to discuss specific programs and funding opportunities. There will then be an open question and answer period – questions can be on any NSF or DBI topic. Join us remotely and bring your questions!

Closed captioning will be available for all office hours.

GRANTED Office Hours

Wednesday, May 22, 2024, 3:00 p.m. – 4:00 p.m.

Heard about NSF Growing Access for Nationally Transformative Equity and Diversity (GRANTED) Initiative and want to learn more? Thinking of submitting a proposal to Program Description (NSF 23-221Y) or Dear Colleague Letter (NSF 23-152)? Then we invite you to GRANTED office hours, held every Wednesday from 3-4PM EDT to meet with the GRANTED team of Program Directors. If you need special accommodations to attend these meeting, please contact Dina Stroud in advance.

Join ZoomGov Meeting

https://nsf.zoomgov.com/j/1615943950?pwd=TG1wYUtOdEIzSTlsdDlub1E2UHlGdz09

Human Networks and Data Science Program Office Hour

Thursday, May 23, 2024, 10:30 a.m. – 12:00 p.m.

Please join the Human Networks and Data Science Program to discuss questions about the program with the program director.

Office hours take place over Zoom, generally on Thursdays. Please see date(s) listed below and note that times listed are in the Eastern time zone.

To join, use the Human Networks and Data Science office hour Zoom link

Office Hours: Intro to America’s Seed Fund at NSF

Thursday, May 23, 2024, 2:00 p.m. – 3:00 p.m.

Join this question-and-answer session to learn more about America’s Seed Fund powered by the National Science Foundation. A Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) program director will answer questions about how to get started, the basics of eligibility and what they look for when they review project pitches.

After Office Hours: Intro to America's Seed Fund

Thursday, May 23, 2024, 7:00 p.m. – 8:00 p.m.

Department of Defense - Congressionally Directed Medical Research Programs General Announcements

Arthritis Research Program Fiscal Year 2024 Request for Information

Congress appropriated $10 million for a new peer reviewed Arthritis Research Program (ATRP) as part of the Department of Defense budget in the 2024 Further Consolidated Appropriations Act. The Congressionally Directed Medical Research Programs (CDMRP) will manage the ATRP according to congressional intent to support research relating to all forms of arthritis, including osteoarthritis, posttraumatic arthritis, and rheumatoid arthritis. (READ MORE)

FY24 ALSRP Resources

The FY24 ALSRP would like to highlight some resources available for potential investigators:

***For FY24, the ALSRP will be using the letter of intent pre-application method for all posted funding mechanisms. Please note that this is a different method than used in previous years!

What is the difference between a letter of intent and a pre-proposal?

CDMRP utilizes two types of pre-application: a letter of intent, often called a LOI, and a pre-proposal. Each program announcement or PA will clearly state which type of pre-application that funding mechanism will be using. (READ MORE)

Vision Research Program (VRP) funding opportunities presentation at the upcoming Association for Research in Vision and Ophthalmology (ARVO) meeting and opportunities to discuss your project with a VRP representative in one-on-one meetings.

National Alliance for Eye and Vision Research (NAEVR) Defense Briefing Special Session

May 6, 2024, 7:00am-8:30am

2AB – Seattle Convention Center – Arch Building

Learn about FY24 VRP funding opportunities and strategies for success

Meet VRP representatives at ARVO

Booth 5007 (Company name: CDMRP Vision Research Program)

Exhibition Hall, Seattle Convention Center

Meeting slots are available on May 5-9. Sign up at https://signup.com/go/jFSwZZe

Fiscal Year 2024 (FY24) pre-announcements and funding announcements for Department of Defense (DOD) programs managed by the Congressionally Directed Medical Research Programs (CDMRP).

FY24 Pre-announcements released:

The Lupus Research Program (LRP) released a pre-announcement for the following funding opportunities:

Idea Award
Impact Award
Transformative Vision Development Award
Transformative Vision Award

To view the pre-announcement visit https://cdmrp.health.mil/pubs/press/2024/24lrppreann

The Parkinson’s Research Program (PRP) released a pre-announcement for the following funding opportunities:

Early Investigator Research Award
Investigator-Initiated Research Award

To view the pre-announcement visit https://cdmrp.health.mil/pubs/press/2024/24prppreann

FY24 Funding announcements released:

The Autism Research Program (ARP) released program announcement for the following funding opportunity:

Discovery Award

To view the program announcements and submit a pre-application visit: https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=577102

The Pancreatic Cancer Research Program (PCARP) released program announcements for the following funding opportunities:

Focused Pilot Award
Idea Development Award
Translational Research Partnership Award

To view the program announcements and submit a pre-application visit: https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=587102

The Prostate Cancer Research Program (PCRP) released program announcements for the following funding opportunities:

Data Science Award
Early Investigator Research Award
Exploration-Hypothesis Development Award
Idea Development Award
Physician Research Award

To view the program announcements and submit a pre-application visit: https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=589103

PCORI – Patient Center Outcome Research Institute

New Funding Opportunity on Advancing the Science of Engagement in Research Opens May 7

On May 7, PCORI's Online System will open for the submission of Letters of Intent (LOI) for the Advancing the Science of Engagement in Research PCORI Funding Announcement (PFA) under Cycle 2 2024.

PCORI seeks to fund studies that build an evidence base on engagement in research, including:

Developing and validating measures to capture the structure/context, process, and outcomes of engagement in research.
Techniques that lead to effective engagement in research.
How effective engagement techniques should be modified and resourced for different contexts, settings, and communities to ensure equity in engagement and research.

LOIs are due on June 4, by 5 pm (ET), and applications are due on Sept. 4 by 5 pm (ET).

Updating PCORI's Engagement in Research Guidance: Foundational Expectations for Partnerships

This webinar offered a first glimpse into PCORI's Foundational Expectations for Partnerships in Research. This new resource is an update to the 2014 PCORI Engagement Rubric and outlines six foundational expectations for meaningful engagement to advance patient-centered comparative clinical effectiveness research (CER). (READ MORE)

BrightFocus Foundation

Alzheimer's Fast Track 2024

October 2-4, 2024, Chicago, Illinois

Description

Learn from experts in the field of Alzheimer’s disease and related dementias at the Alzheimer’s Fast Track workshop. Designed for graduate students, postdoctoral fellows, and other early-career scientists focused on Alzheimer’s disease research, this immersive learning experience will accelerate your knowledge, expertise, and visibility in this exciting field.

October 2-4, 2024
Chicago, Illinois
Official pre-meeting to Society for Neuroscience

Network with peers and expert scientists
Learn how to write a grant with mentorship from our chairs and speakers
Present a group mock grant proposal to a review panel

American Heart Association

AHA Predoctoral Fellowship

Proposal deadline: Wednesday, September 4, 2024

Enhances the training of promising students in pre-doctoral or clinical health professional degree training programs and who intend careers as scientists, physician-scientists or other clinician-scientists, or related careers aimed at improving global health and wellbeing. Within this award, additional collaboration money has been designated through the AHA/CHF Congenital Heart Defect Research Awards and by the Barth Syndrome Foundation and California Walnut Commission.

AHA Postdoctoral Fellowship

Proposal deadline: Thursday, September 5, 2024
Enhances the training of postdoctoral applicants who are not yet independent. The applicant must be embedded in an appropriate investigative group with the mentorship, support, and relevant scientific guidance of a research mentor. Within this award, additional collaboration money has been designated through the AHA/CHF Congenital Heart Defect Research Awards and AHA/VIVA Physician Research Award and by the Barth Syndrome Foundation and California Walnut Commission.

Career Development Award

Proposal deadline: Wednesday, December 5, 2024
Supports highly promising healthcare and academic professionals in the early years of first professional appointment to assure the applicant’s future success as a research scientist in the field of cardiovascular and/or cerebrovascular disease research.

Research Supplement to Promote Diversity in Science

Proposal deadline: Thursday, February 6, 2025
To enable current AHA awardees to identify and serve as mentors for predoctoral and postdoctoral fellows from underrepresented groups in science and medicine.