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Appendix B Course Descriptions

Core Curriculum

Applied Biostatistics (BIOS 601).  Introduces parametric and nonparametric statistical methodology, including descriptive measures, elementary probability, estimation, hypothesis testing, confidence intervals, common nonparametric methods, and base contingency table analysis.  Empirically demonstrates underlying theory.  Required course for Social & Behavioral and Occupational & Environmental Health Sciences tracks of WVU Public Health Sciences Ph.D. program.

Applied Biostatistics Lab (BIOS 602).  Introduces the use of statistical software (SAS, R) to perform basic analyses.  Required course for Social & Behavioral and Occupational & Environmental Health Sciences tracks of WVU Public Health Sciences Ph.D. program.

Applied Pharmacology (PCOL 549).  Effect of drugs in humans with emphasis on application of drugs relevant to health professionals.

Fundamentals of Physiology (PSIO 743).  Normal, with appropriate pathological deviations, of human biological function at molecular, cellular, organ, organ system, and whole organism levels. 

General Biochemistry (BIOC 531).  General introduction to biochemical compounds, processes, and concepts.  Specific topics such as the biochemistry of various diseased states, enzyme mechanisms, therapeutic use of enzyme inhibitors, effects of drugs on various metabolic pathways, signal transduction, drug biotransformation, and drug resistance provide basic biochemical information for subsequent, more in-depth courses. 

Graduate Seminar in Basic Sciences (BMS 796).  Seminars will be selected from those offered weekly throughout the basic science departments.  Students must attend 8 seminars over the course of the semester.  These schedules are published well in advance facilitating student choice.  An additional part of this course is bi-weekly journal club.  The students will meet as a group to discuss an article selected from the scientific literature and relevant to the seminars occurring that semester.  This activity will build their critical thinking skills.

Graduate Seminar in Public Health Sciences (PUBH 696).  Seminars will be selected from those offered throughout the Public Health departments.  Students must attend 7 seminars over the course of the semester.  An additional part of this course is bi-weekly journal club.  The students will meet as a group to discuss an article selected from the scientific literature and relevant to the seminars occurring that semester.  This activity will build their critical thinking skills.

Independent Study (BMS 795).  The faculty mentors will supervise the student in an independent research project developed based on the results of their individual development plan and their area of emphasis.  Student projects will be completed during the summer semester. 

Public Health Epidemiology (EPID 601).   Examines mortality and morbidity trends, disease and injury models, data sources classification, measures of frequency and association, research design, causal assessment, data interpretation, and screening from an epidemiological perspective. 

Social and Behavioral Theory (SBHS 601).  Role of individual behavior in attaining health.  Integration of the concepts of health education and behavioral science to facilitate changes in health behavior. 

Suggested Electives:

Clinical Research Methods (PUBH 662).  Work with faculty and staff in the Emergency Department of Ruby Memorial Hospital and participate in a variety of research projects. Has a didactic component that focuses on clinical research design and clinical "shifts" in the Emergency Department where students learn how to identify, approach, consent, and enroll patients into clinical studies. Stresses data collection methods, research design, professional responsibility, and independent thinking.  Research techniques that can be applied to a wide variety of cardiovascular, neurological, trauma and social services emergency care research, and experience developing practicum projects.

Drugs: Bench to Market (PHAR 779).  Process of drug discovery to the development of new forms for therapeutic use.  Topics covered include drug design/discovery, pharmacokinetics and dynamics, pharmaceutics, and industry pharmacy.

Environmental Health (OEHS 601).  Responsibilities and roles of public health work force in identifying, managing and preventing casualties from environmental causes in air, water, soil, food, pesticides, and related subjects.  WV policy dilemmas.

Ethical and Regulatory Aspects of Clinical Research (PHAR 758).  History, guidance, and framework for ethical clinical research; IRB review, informed consent and investigator panel; subject selection, coercion and undue inducement and ethics of research with children; risks and benefits, research with adults who cannot consent and participant panel; ethics and international research; ethics of randomized clinical trials, the use of placebo in trials and conflicts of interest; research use of stored tissue and data and incidental findings, and RCR sessions covering topics such as mentoring and research misconduct.  Ethics is emphasized in medical and dental curricula and graduate curricula.

Immunology and Biotechnology (PHAR 709).  Basic functions of the immune system, pharmaceutical applications of biotechnology, and introduction to chemotherapy of infections.

Molecular Diagnosis in Public Health (OEHS 770).  Overview of interdisciplinary approaches in molecular diagnosis and prognosis for personalized patient care.  Knowledge of genome-wide association studies.  Description of methodologies in applying gene profiling for personalized therapy.  Latest advances in molecular biology, cell biology, pharmacology, high throughput microarrays, translational and pre-clinical research, and commonly used biostatistics techniques and bioinformatics tools.  Techniques for research design, data retrieval from public databases (i.e., GEO, NCBI, SEER, and ONCOMINE), and experimental analysis and interpretation.

Pathology and Anatomy (PATH 603).  Gross and microscopic human anatomy including embryology, histology and microanatomy lab.  Anatomy is taught in the 1st-year curricula to medical and dental students.

Principles of Clinical Trials (EPID 625).  Core elements of clinical trials and critical evaluation of clinical trial literature; designing original clinical trials and developing grant proposals in clinical trial research.

Public Health Toxicology (OEHS 622).  Principles of toxicology that pertain to human health and the environment and integration of these principles into public health practice.

Graduate Physiology (PSIO 750).  Survey of quantitative level of basic concepts and experimental approaches to cellular, endocrine, and neural mechanisms controlling physiological processes.