Benoit Driesschaert, Ph.D.
Dr. Driesschaert holds a master degree from the Université catholique de Louvain in organic chemistry (2005), a master after master degree (2007) and a Ph.D. from the same university (2013). His Ph.D. focused on the development of EPR spin labels (advisors: Pr. Bernard Gallez and Pr. Jacqueline Marchand-Brynaert). In 2014, he moved to the Ohio State University to expand his knowledge in EPR spectroscopy (Pr. Jay Zweier and Pr. Valery Khramtsov). In 2015, he moved with Valery Khramtsov to the West Virginia University to work on the development of multifunctional EPR probes.
The sphere of interest:
Benoit has an extensive experience in the synthesis of stable triarylmethyl radicals used to measure oxygen and pH by EPR. He was also involved in projects dealing with the synthesis of RGD petidomimetics and RGD-targeted NMR and EPR probes. His current interests are the development of innovative EPR/NMR probes allowing systemic delivery. He is also involved in the development of new EPR spin traps.
· Driesschaert, B., Bobko, A.A., Eubank, T.D., Samouilov, A., Khramtsov, V.V., Zweier, J.L., Poly-arginine conjugated triarylmethyl radical as intracellular spin label, Bioorg. Med. Chem. Lett. 2015, 26(7), 1742.
· Driesschaert, B., Levêque, P., Gallez, B., Marchand-Brynaert, Tetrathiatriarylmethyl radicals conjugated to an RGD-peptidomimetic, J. Eur. J. Org. Chem.2014, 36, 8077.
· Driesschaert, B., Levêque, P., Gallez, B., Marchand-Brynaert, J., RGD-conjugated triarylmethyl radical as probe for electron paramagnetic imaging, Tet. Lett. 2013, 54(44), 5924.
· Driesschaert, B., Marchand, V., Levêque, P., Gallez, B., Marchand-Brynaert, J., A phosphonated triarylmethyl radical as a probe for measurement of pH by EPR, Chem. Commun. 2012, 48(34), 4049.
· Driesschaert, B., Robiette, R., Lucaccioni, F., Gallez, B., Marchand-Brynaert, J., Chiral properties of tetrathiatriarylmethyl spin probes, Chem. Commun. 2011, 47(16), 4793.